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EHU017801

Sigma-Aldrich

MISSION® esiRNA

targeting human CNTNAP1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

TGGTCAACTGGTCAACCTGACTCTGGTGGAGGGCCGGCGGCTTGGATTCTATGCTGAGGTCCTCTTTGATACATGTGGCATCACTGATAGGTGCAGCCCTAACATGTGTGAGCATGATGGACGCTGCTACCAGTCTTGGGATGACTTCATTTGCTACTGCGAACTGACGGGCTACAAGGGAGAGACCTGCCACACACCTTTGTATAAGGAATCCTGTGAGGCTTATCGGCTCAGTGGGAAAACTTCTGGAAACTTCACCATTGATCCTGATGGCAGTGGCCCCCTGAAGCCATTTGTAGTGTACTGTGATATCCGAGAGAACCGAGCGTGGACAGTTGTGCGGCATGACAGGCTGTGGACAACTCGAGTGACAGGTTCCAGCATGGAGCGGCCATTCCTGGGGGCTATCCAGTACTGGAATGCATCCTGGGAGGAAGTCAGTGCCCTTGCCAATGCTTCCCAGCATTGTGAACAGTGGATCGAGTTCTCCTGCTACAATTCCCG

Ensembl | human accession no.

ENSG00000108797

NCBI accession no.

NM_003632

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... CNTNAP1(8506) , CNTNAP1(8506)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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Wenlong Zhang et al.
Theranostics, 10(7), 3000-3021 (2020-03-21)
Rationale: Contactin-associated protein-like 4 (CNTNAP4) belongs to the neurexin superfamily and has critical functions in neurological development and synaptic function. Loss of CNTNAP4 in interneurons has been linked to autism, schizophrenia, and epilepsy. CNTNAP4 is also highly enriched in dopaminergic
Wei-Dong Zhao et al.
Nature communications, 9(1), 2296-2296 (2018-06-14)
Escherichia coli is the leading cause of neonatal Gram-negative bacterial meningitis, but the pathogenesis of E. coli meningitis remains elusive. E. coli penetration of the blood-brain barrier (BBB) is the critical step for development of meningitis. Here, we identify Caspr1

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