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EHU121521

Sigma-Aldrich

MISSION® esiRNA

targeting human NME3

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5 MG
$221.00
25 MG
$877.00

$221.00


Estimated to ship onMarch 18, 2025



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5 MG
$221.00
25 MG
$877.00

About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

$221.00


Estimated to ship onMarch 18, 2025


description

Powered by Eupheria Biotech

Quality Level

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

AGGAAGGGCTTCAAGTTGGTGGCGCTGAAGCTGGTGCAGGCCTCCGAGGAGCTGCTGCGTGAGCACTACGCCGAGCTGCGTGAACGCCCGTTCTACGGCCGCCTTGTCAAGTATATGGCCTCCGGGCCGGTGGTGGCCATGGTATGGCAGGGGCTGGACGTGGTGCGCACCTCGCGGGCGCTCATCGGAGCCACGAACCCGGCCGACGCCCCGCCCGGCACCATCCGCGGGGATTTCTGCATCGAGGTTGGCAAGAACCTGATTCACGGCAGCGACTCGGTGGAGAGTGCCCGCCGCGAGATCGCTCTCTGGTTCCGCGCAGACGAGCTCCTCTGCTGGGAGGACAGCGCTGGGCACTGGCTGTATGAGTAGCCCGGCAGATGCGCGTCACAGAGGCTCTCACAC

Ensembl | human accession no.

NCBI accession no.

shipped in

ambient

storage temp.

−20°C

Gene Information

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RAB0725RAB0648RAB0738
Gene Information

human ... NPPB(4879)

Gene Information

human ... PPY(5539)

Gene Information

human ... FGA(2243)

Gene Information

human ... TGFBR3(7049)

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.14 ng/mL
standard curve range: 0.137-100 ng/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 4 pg/mL
standard curve range: 4.10-1000 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 0.08 pg/mL
standard curve range: 0.082-60 pg/mL

assay range

inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 40 pg/mL
standard curve range: 40.96-10000 pg/mL

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)
sample type urine

input

sample type serum
sample type cell culture supernatant(s)
sample type plasma

input

sample type serum
sample type urine
sample type plasma
sample type cell culture supernatant(s)

input

sample type serum
sample type plasma
sample type cell culture supernatant(s)

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

detection method

colorimetric

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

technique(s)

ELISA: suitable

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

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Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable


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    Chih-Wei Chen et al.
    International journal of molecular sciences, 21(14) (2020-07-28)
    NME3 is a member of the nucleoside diphosphate kinase (NDPK) family that binds to the mitochondrial outer membrane to stimulate mitochondrial fusion. In this study, we showed that NME3 knockdown delayed DNA repair without reducing the cellular levels of nucleotide

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