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EMU056231

Sigma-Aldrich

MISSION® esiRNA

targeting mouse Runx1t1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51

description

Powered by Eupheria Biotech

Quality Level

100

product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GCACTCAGAACATCCAAGCAAGCGACCATGCACTATTAGCCCAGGCCAGCGGTACAGTCCAAATAATGGCTTATCCTACCAGCCAAATGGCCTGCCTCACCCCACCCCACCTCCACCTCAGCATTACCGATTGGATGATATGGCCATTGCCCACCACTACAGGGACTCCTATCGACACCCCAGCCACAGGGACCTCAGGGACAGAAATAGACCTATGGGGTTACATGGCACACGTCAAGAAGAAATGATTGACCACAGACTAACAGACAGAGAATGGGCAGAAGAGTGGAAACATCTCGATCATCTGTTAAACTGCATCATGGACATGGTGGAGAAGACAAGACGATCCCTCACTGTACTAAGACGATGTCAGGAAGCGGACCGGGAAGAACTGAATTACTGGATACGGCGGTACAGTGATGCTGAGGACTTAAAAAAGGGTGGCAGCAGTAGCAGCAGCCACTCCAGGCAGCAGAGTCCTGTCAATCCAGACCCAGT

Ensembl | mouse accession no.

ENSMUSG00000006586

NCBI accession no.

NM_009822

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... RUNX1T1(12395) , Runx1t1(12395)

General description

MISSION® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

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O Breig et al.
Leukemia, 28(6), 1271-1279 (2013-12-18)
The oncogenic fusion protein AML1-ETO, also known as RUNX1-RUNX1T1 is generated by the t(8;21)(q22;q22) translocation, one of the most frequent chromosomal rearrangements in acute myeloid leukemia (AML). Identifying the genes that cooperate with or are required for the oncogenic activity

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