Skip to Content
MilliporeSigma
All Photos(1)

Documents

F1395

Sigma-Aldrich

β-L-Fucose 1-phosphate bis(cyclohexylammonium) salt

≥98%

Synonym(s):

6-Deoxy-β-L-galactose 1-phosphate

Sign Into View Organizational & Contract Pricing
All Photos(1)

About This Item

Empirical Formula (Hill Notation):
C6H11O8P · 2C6H14N
Molecular Weight:
442.48
MDL number:
MFCD22681514
UNSPSC Code:
12352201
PubChem Substance ID:
329799679
NACRES:
NA.25

assay

≥98%

form

powder

technique(s)

thin layer chromatography (TLC): suitable

solubility

H2O: soluble 50 mg/mL, clear, colorless

storage temp.

−20°C

SMILES string

NC1CCCCC1.NC2CCCCC2.C[C@@H]3O[C@H](OP(O)(O)=O)[C@@H](O)[C@H](O)[C@@H]3O

InChI

1S/2C6H13N.C6H13O8P/c2*7-6-4-2-1-3-5-6;1-2-3(7)4(8)5(9)6(13-2)14-15(10,11)12/h2*6H,1-5,7H2;2-9H,1H3,(H2,10,11,12)/t;;2-,3+,4+,5-,6+/m..0/s1

InChI key

FQMPFZHILABVMA-PEJHDPODSA-N

Application

β-L-Fucose 1-phosphate is suitable as both substrate and product to identify, differentiate and characterize GTP fucose pyrophosphorylase(s) (GFPP; fucose-1-phosphate guanylyltransferases) involved in the formation of the nucleotide-sugar GDP-beta-l-fucose and other fucosylation donor substrates such as 3,3′-Diaminobenzidine (GDP)-β-l-fucose. β-L-Fucose 1-phosphate may be used to generate new fucosylation donor substrates for use in glycan fucosylation research.

Other Notes

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

GDP-L-fucose pyrophosphorylase. Purification, cDNA cloning, and properties of the enzyme.
Pastuszak I, Ketchum C, Hermanson G, et al.
The Journal of Biological Chemistry, 4273, 30165-30174 (1998)
Leonie Engels et al.
Glycobiology, 24(2), 170-178 (2013-11-20)
Fucosyltransferases (FucTs) are essential tools for the synthesis of fucosylated glycoconjugates. Multistep enzyme catalysis of fucosylated glycans is not limited as long as isolated and well-characterized FucTs are available. The present paper introduces a novel bacterial α1,2-FucT of the glycosyltransferase
Bing Ma et al.
Glycobiology, 16(12), 158R-184R (2006-09-16)
Fucosylated carbohydrate structures are involved in a variety of biological and pathological processes in eukaryotic organisms including tissue development, angiogenesis, fertilization, cell adhesion, inflammation, and tumor metastasis. In contrast, fucosylation appears less common in prokaryotic organisms and has been suggested
Toshihisa Kotake et al.
The Journal of biological chemistry, 283(13), 8125-8135 (2008-01-18)
Monomeric sugars generated during the metabolism of polysaccharides, glycoproteins, and glycolipids are imported to the cytoplasm and converted to respective nucleotide sugars via monosaccharide 1-phosphates, to be reutilized as activated sugars. Because L-fucose (L-Fuc) is activated mainly in the form
Stephen Quirk et al.
Biochemistry, 44(39), 13172-13178 (2005-09-28)
GTP-l-fucose pyrophosphorylase(GFPP) catalyzes the reversible formation of the nucleotide-sugar GDP-beta-l-fucose from guanosine triphosphate and beta-l-fucose-1-phosphate. The enzyme functions primarily in the mammalian liver and kidney to salvage free fucose during the breakdown of glycoproteins and glycolipids. GFPP shares little primary
View All Related Papers

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service