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I1656

Sigma-Aldrich

Idarubicin hydrochloride

solid

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Synonym(s):
(7S-cis)-9-Acetyl-7-[(3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,9,11-trihydroxy-5,12-naphthacenedione, 4-Demethoxydaunorubicin hydrochloride, DMDR, IMI-30, Idamycin
Empirical Formula (Hill Notation):
C26H27NO9 · HCl
CAS Number:
Molecular Weight:
533.95
EC Number:
MDL number:
PubChem Substance ID:
NACRES:
NA.77

form

solid

Quality Level

originator

Johnson & Johnson

shipped in

wet ice

storage temp.

2-8°C

SMILES string

[H][C@@]1(C[C@@](O)(Cc2c(O)c3C(=O)c4ccccc4C(=O)c3c(O)c12)C(C)=O)O[C@H]5C[C@H](N)[C@H](O)[C@H](C)O5

InChI

1S/C26H27NO9/c1-10-21(29)15(27)7-17(35-10)36-16-9-26(34,11(2)28)8-14-18(16)25(33)20-19(24(14)32)22(30)12-5-3-4-6-13(12)23(20)31/h3-6,10,15-17,21,29,32-34H,7-9,27H2,1-2H3/t10-,15-,16-,17-,21+,26-/m0/s1

InChI key

XDXDZDZNSLXDNA-TZNDIEGXSA-N

Gene Information

human ... TOP2A(7153)

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This Item
UC2111335701PHR2704
Sigma-Aldrich

I1656

Idarubicin hydrochloride

7-Hydroxywarfarin

UC211

7-Hydroxywarfarin

USP

1335701

Idarubicin

Supelco

PHR2704

Idarubicin hydrochloride

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

-10 to -25°C

shipped in

wet ice

shipped in

-

shipped in

-

shipped in

-

originator

Johnson & Johnson

originator

-

originator

-

originator

-

Gene Information

human ... TOP2A(7153)

Gene Information

-

Gene Information

human ... TOP2A(7153)

Gene Information

-

application

Idarubicin is an anthracycline antibiotic that is an anti-leukemia agent with higher DNA binding capacity and greater cytotoxicity than daunorubicin.

Biochem/physiol Actions

Topoisomerase II inhibitor

Features and Benefits

This compound is a featured product for Apoptosis research. Click here to discover more featured Apoptosis products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.
This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

pictograms

Skull and crossbonesHealth hazard

signalword

Danger

Hazard Classifications

Acute Tox. 2 Oral - Carc. 2 - Repr. 1B

Storage Class

6.1A - Combustible, acute toxic Cat. 1 and 2 / very toxic hazardous materials

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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