MilliporeSigma
All Photos(1)

Documents

L7634

Sigma-Aldrich

α-Lactose-Agarose

saline suspension

Sign Into View Organizational & Contract Pricing

Synonym(s):
alpha-lactose resin
MDL number:

biological source

bovine milk

Quality Level

form

saline suspension

technique(s)

affinity chromatography: suitable

matrix

6% beaded agarose

matrix activation

divinyl sulfone

matrix attachment

hydroxyl

matrix spacer

5 atoms

capacity

6-25 mg/mL binding capacity (lectin from Arachis hypogaea)

suitability

suitable for chromatography

storage temp.

2-8°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
I4758P1406P7700
Sigma-Aldrich

L7634

α-Lactose-Agarose

Iminodiacetic acid Agarose saline suspension

I4758

Iminodiacetic acid Agarose

Protein A–Agarose lyophilized powder

P1406

Protein A–Agarose

Protein G–Agarose lyophilized powder, Contains lactose stabilizers that must be removed prior to use.

P7700

Protein G–Agarose

storage temp.

2-8°C

storage temp.

2-8°C

storage temp.

−20°C

storage temp.

−20°C

matrix

6% beaded agarose

matrix

cross-linked 4% beaded agarose

matrix

Cross-linked 4% beaded agarose

matrix

cross-linked 4% beaded agarose

matrix activation

divinyl sulfone

matrix activation

epoxy

matrix activation

cyanogen bromide

matrix activation

cyanogen bromide

matrix attachment

hydroxyl

matrix attachment

amino

matrix attachment

amino

matrix attachment

amino

matrix spacer

5 atoms

matrix spacer

12 atoms

matrix spacer

1 atom

matrix spacer

1 atom

Application

α-Lactose-agarose has been used:
  • in protein chromatography to purify galectins from lysed bacteria cells
  • to capture ricin based on lectin-carbohydrate affinity
  • to study microneme proteins and host-parasite cell surface receptors

α-lLactose-agarose is used in protein chromatography, affinity chromatography and carbohydrate matrices. α--Lactose-agarose has been used to study microneme proteins and host-parasite cell surface receptors.

Physical form

Suspension in 0.15 M NaCl, 0.01 M sodium phosphate, pH 6.8, containing 0.02% sodium azide

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 7

1 of 7

Sepharose™ 4B 45-165 μm bead diameter

Sigma-Aldrich

4B200

Sepharose 4B

Lactose tested according to Ph. Eur.

Sigma-Aldrich

17814

Lactose

D-Lactose monohydrate ACS reagent

Sigma-Aldrich

L254

D-Lactose monohydrate

Lactose (anhydrous) European Pharmacopoeia (EP) Reference Standard

A1206000

Lactose (anhydrous)

Divinyl sulfone contains hydroquinone as inhibitor, ≥96%

Sigma-Aldrich

V3700

Divinyl sulfone

Timestrip Plus™ 8 °C

Supelco

08168

Timestrip Plus 8 °C

Christophe Dussouy et al.
Chemical biology & drug design, 96(4), 1123-1133 (2020-03-29)
Galectins play key roles in numerous biological processes. Their mode of action depends on their localization which can be extracellular, cytoplasmic, or nuclear and is partly mediated through interactions with β-galactose containing glycans. Galectins have emerged as novel therapeutic targets
C Allison Gray et al.
Proceedings of the National Academy of Sciences of the United States of America, 101(21), 7982-7987 (2004-05-19)
Secretions of the uterus support survival and growth of the conceptus (embryo/fetus and associated membranes) during pregnancy. Galectin-15, also known as OVGAL11 and a previously uncharacterized member of the galectin family of secreted beta-galactoside lectins containing a conserved carbohydrate recognition
Nadine Keller et al.
Infection and immunity, 72(8), 4791-4800 (2004-07-24)
Microneme proteins have been shown to play an important role in the early phase of host cell adhesion, by mediating the contact between the parasite and host cell surface receptors. In this study we have identified and characterized a lectin-like
E V Lourenço et al.
Glycobiology, 11(7), 541-547 (2001-07-12)
Host cell invasion by Toxoplasma gondii is a multistep process with one of the first steps being the apical release of micronemal proteins that interact with host receptors. We demonstrate here that micronemal protein 1 (MIC1) is a lactose-binding lectin.
C M Klier et al.
Microbiology (Reading, England), 143 ( Pt 3), 835-846 (1997-03-01)
The species Actinomyces serovar WVA963 is among the 20 bacteria most frequently isolated from human subgingival plaque. The interactions of this species with streptococci are inhibited by lactose, a function associated with type 2 fimbrial surface structures in Actinomyces naeslundii.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service