M0534
5-Methyl-DL-tryptophan
tryptophan analog
Synonym(s):
5-Methyltryptophan
About This Item
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Quality Level
assay
≥97% (TLC)
form
powder
color
white to faint yellow
mp
280-282 °C
application(s)
peptide synthesis
storage temp.
2-8°C
SMILES string
Cc1ccc2[nH]cc(CC(N)C(O)=O)c2c1
InChI
1S/C12H14N2O2/c1-7-2-3-11-9(4-7)8(6-14-11)5-10(13)12(15)16/h2-4,6,10,14H,5,13H2,1H3,(H,15,16)
InChI key
HUNCSWANZMJLPM-UHFFFAOYSA-N
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Related Categories
Application
- Amelioration of colitis through modulation of gut microbiota: The metabolite 5-Methyl-ᴅʟ-tryptophan (5-MT), derived from Angelica sinensis polysaccharides, was found to ameliorate colitis by modulating gut microbiota and the TLR4/MyD88/NF-κB signaling pathway. This suggests a potential application of 5-MT in inflammatory bowel disease research and therapy (Zou et al., 2023).
- Enzymatic synthesis of tryptophan derivatives: A study on the one-pot enantioselective synthesis of (S)-spirobrassinin and non-natural (S)-methylspirobrassinin from amino acids highlights a method using a turnip enzyme. This research outlines a novel approach to synthesizing tryptophan derivatives, potentially useful in biochemical assays (Ryu et al., 2021).
Biochem/physiol Actions
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
Certificates of Analysis (COA)
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