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Key Documents

M1442

Sigma-Aldrich

MOPS solution

BioPerformance Certified, 1 M, suitable for cell culture

Synonym(s):

3-(N-morpholino)propanesulfonic acid buffer solution

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About This Item

MDL number:
UNSPSC Code:
12161700
PubChem Substance ID:
NACRES:
NA.25

grade

BioPerformance Certified
for molecular biology

Quality Level

sterility

sterile; 0.2 μm filtered

form

solution

concentration

1 M

technique(s)

cell culture | mammalian: suitable

impurities

Bioburden, tested
DNase, RNase, Protease, none detected
endotoxin, tested

useful pH range

6.5-7.9

cation traces

Fe: ≤5 ppm
heavy metals (as Pb): ≤5 ppm

InChI

1S/C6H13NO4S/c8-12(9,10)6-3-7-1-4-11-5-2-7/h1-6H2,(H,8,9,10)

InChI key

SXGZJKUKBWWHRA-UHFFFAOYSA-N

Application

<ul>
<li><strong>Buffers more than buffering agent: introducing a new class of stabilizers for the protein BSA:</strong> This study explores the role of MOPS buffer in stabilizing protein structures, contributing to enhanced reproducibility in biotechnological applications such as protein formulation and drug development (Gupta et al., 2015).</li>
<li><strong>Self crowding of globular proteins studied by small-angle x-ray scattering:</strong> This article highlights the use of MOPS buffer to maintain pH stability during the study of protein interactions using x-ray scattering techniques, critical for understanding protein behavior in various biotechnological processes (Goldenberg and Argyle, 2014).</li>
<li><strong>Investigation of the affinity and selectivity of avian prion hexarepeat peptides for physiological divalent metal ions:</strong> MOPS buffer is used to examine the binding characteristics of prion proteins, aiding in the development of therapeutic agents and understanding metal-protein interactions in neurodegenerative diseases (Shields and Franklin, 2007).</li>
<li><strong>Characterization of the monomer-dimer equilibrium of human cytomegalovirus protease by kinetic methods:</strong> This research employs MOPS buffer to study the kinetic properties of viral proteases, which is fundamental for antiviral drug discovery and molecular biology studies focused on viral replication mechanisms (Khayat et al., 2004).</li>
</ul>

Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


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