MilliporeSigma
All Photos(4)

Documents

M7504

Sigma-Aldrich

Mannan from Saccharomyces cerevisiae

prepared by alkaline extraction

Sign Into View Organizational & Contract Pricing

Synonym(s):
D-Mannan
CAS Number:
MDL number:
NACRES:
NA.25

biological source

bakers yeast (whole cell)

Quality Level

form

powder

optical activity

[α]/D 73 to 89 °, c = 1% (w/v) in water

impurities

<1.0% Low molecular weight saccharides (TLC)

color

beige

solubility

water: ~50 g/L

cation traces

Na: <2%

storage temp.

2-8°C

Looking for similar products? Visit Product Comparison Guide

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
G5011YSC2YSC1
vibrant-m

YSC2

Yeast from Saccharomyces cerevisiae

vibrant-m

YSC1

Yeast from Saccharomyces cerevisiae

solubility

water: ~50 g/L

solubility

water: 9.80-10.20 mg/mL, turbid, colorless to light yellow

solubility

-

solubility

-

biological source

bakers yeast (whole cell)

biological source

bakers yeast (S. cerevisiae)

biological source

Saccharomyces cerevisiae

biological source

Saccharomyces cerevisiae

form

powder

form

powder

form

powder or solid

form

powder or solid

impurities

<1.0% Low molecular weight saccharides (TLC)

impurities

-

impurities

-

impurities

-

cation traces

Na: <2%

cation traces

-

cation traces

-

cation traces

-

General description

Mannan is the main component of yeast cell wall polysaccharides broadly present in nature, such as in plants, bacteria, yeasts, and other organisms. It comprises a highly branched complex carbohydrate, an α-1,6 backbone with α-1,2- and α-1,3-attached mannose side chains.

Application

Mannan from Saccharomyces cerevisiae has been used to coat the microtiter wells to quantify the levels of mannose-binding lectin (MBL) using a mannan-binding enzyme-linked immunosorbent assay (ELISA).
Mannan from Saccharomyces cerevisiae has been used in a study to assess nonopsonic uptake of Mycobacterium avium complex by human monocytes and alveolar macrophages. It has also been used in a study to investigate new lectins from bulbs of Croccus sativum.

Biochem/physiol Actions

Mannan exhibits several biological properties, including antiproliferative, antioxidant, and immunomodulatory. It is used as a hardener ingredient and as an emulsion stabilizer. Mannan is also involved in the inhibition of pathogen adherence, regulation of bacterial growth, and enhancement of the immune response.

Preparation Note

Prepared by method of Haworth.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Already Own This Product?

Documents related to the products that you have purchased in the past have been gathered in the Document Library for your convenience.

Visit the Document Library

Difficulty Finding Your Product Or Lot/Batch Number?

Product numbers are combined with Pack Sizes/Quantity when displayed on the website (example: T1503-25G). Please make sure you enter ONLY the product number in the Product Number field (example: T1503).

Example:

T1503
Product Number
-
25G
Pack Size/Quantity

Additional examples:

705578-5MG-PW

PL860-CGA/SHF-1EA

MMYOMAG-74K-13

1000309185

enter as 1.000309185)

Having trouble? Feel free to contact Technical Service for assistance.

Lot and Batch Numbers can be found on a product's label following the words 'Lot' or 'Batch'.

Aldrich Products

  • For a lot number such as TO09019TO, enter it as 09019TO (without the first two letters 'TO').

  • For a lot number with a filling-code such as 05427ES-021, enter it as 05427ES (without the filling-code '-021').

  • For a lot number with a filling-code such as STBB0728K9, enter it as STBB0728 without the filling-code 'K9'.

Not Finding What You Are Looking For?

In some cases, a COA may not be available online. If your search was unable to find the COA you can request one.

Request COA

Customers Also Viewed

Slide 1 of 5

1 of 5

Y Oda et al.
Biological & pharmaceutical bulletin, 16(10), 978-981 (1993-10-01)
Four isolectins were isolated from bulbs of Croccus sativum (saffron), using affinity chromatography on mannan-Sepharose 4B, gel filtration and ion-exchange column chromatography in the presence of 8 M urea. The relative molecular masses of these lectins were determined by gel
Michael L Patnode et al.
Cell, 179(1), 59-73 (2019-09-21)
Development of microbiota-directed foods (MDFs) that selectively increase the abundance of beneficial human gut microbes, and their expressed functions, requires knowledge of both the bioactive components of MDFs and the mechanisms underlying microbe-microbe interactions. Here, gnotobiotic mice were colonized with
J A Roecklein et al.
The Journal of laboratory and clinical medicine, 119(6), 772-781 (1992-06-11)
The uptake of Mycobacterium avium complex (MAC) microorganisms by human peripheral blood monocytes (PBMs) and alveolar macrophages (AMs) is not well understood. We have previously shown, under opsonic conditions, that humoral factors are important in mediating the uptake of MAC
Polysaccharides. Part XXIV. Yeast mannan.
Haworth, W.N., et al.
Journal of the Chemical Society, 784-791 (1937)
Geelsu Hwang et al.
PLoS pathogens, 13(6), e1006407-e1006407 (2017-06-16)
Candida albicans is frequently detected with heavy infection by Streptococcus mutans in plaque-biofilms from children with early-childhood caries (ECC). This cross-kingdom biofilm contains an extensive matrix of extracellular α-glucans that is produced by an exoenzyme (GtfB) secreted by S. mutans.

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service