M7504

Mannan from Saccharomyces cerevisiae

prepared by alkaline extraction

• Synonym(s): D-Mannan
• CAS Number: 9036-88-8
• MDL number: MFCD00131574
• UNSPSC Code: 12352201
• NACRES: NA.25

Properties

• biological source: bakers yeast (whole cell)
• Quality Level: 300
• form: powder
• optical activity: [α]/D 73 to 89 °, c = 1% (w/v) in water
• impurities: <1.0% Low molecular weight saccharides (TLC)
• color: beige
• solubility: water: ~50 g/L
• cation traces: Na: <2%
• storage temp.: 2-8°C

Description

General description

Mannan is the main component of yeast cell wall polysaccharides broadly present in nature, such as in plants, bacteria, yeasts, and other organisms. It comprises a highly branched complex carbohydrate, an α-1,6 backbone with α-1,2- and α-1,3-attached mannose side chains.

Application

Mannan from Saccharomyces cerevisiae has been used to coat the microtiter wells to quantify the levels of mannose-binding lectin (MBL) using a mannan-binding enzyme-linked immunosorbent assay (ELISA).

Mannan from Saccharomyces cerevisiae has been used in a study to assess nonopsonic uptake of Mycobacterium avium complex by human monocytes and alveolar macrophages. It has also been used in a study to investigate new lectins from bulbs of Croccus sativum.

Biochem/physiol Actions

Mannan exhibits several biological properties, including antiproliferative, antioxidant, and immunomodulatory. It is used as a hardener ingredient and as an emulsion stabilizer. Mannan is also involved in the inhibition of pathogen adherence, regulation of bacterial growth, and enhancement of the immune response.

Preparation Note

Prepared by method of Haworth.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)