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MAK315

Sigma-Aldrich

Oxalate Assay Kit

sufficient for 100 colorimetric tests

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NACRES:
NA.84

detection method

colorimetric

relevant disease(s)

genitourinary disorders

storage temp.

−20°C

Related Categories

General description

Oxalate or Oxalic Acid is a metabolic breakdown product of the Kreb′s Cycle in eukaryotes, and the glyoxylate cycle in other microorganisms. It can be found in the urine of humans and other mammals. Oxalate concentration can be used as a measure of kidney function where a high level of oxalate is an indicator for kidney stones which are primarily made of the insoluble salt calcium oxalate. Measuring oxalate is more accurate than measuring calcium as a marker for kidney stones because calcium is excreted at high concentrations even in normal urine.

Features and Benefits

Compatible with high-throughput handling systems.

Suitability

Suitable for the quantitative determination of oxalate (oxalic acid) in urine, animal and plant tissue samples.

Principle

Simple, direct and high-throughput assays for measuring oxalate concentration find wide applications. This oxalate assay kit uses a single Working Reagent that combines the oxalate oxidase reaction and color reaction in one step. The change in color intensity of the reaction product at 595 nm is directly proportional to oxalate in the sample.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Natalia Stepanova et al.
The Korean journal of internal medicine (2021-06-26)
It was hypothesized that oxalate might be strongly involved in atherogenesis and the inflammatory pathway that could result in an increased risk of cardiovascular disease (CVD) in end-stage renal disease (ESRD) patients. Therefore, this study aimed to address two primary
Natalia Stepanova et al.
In vivo (Athens, Greece), 36(2), 925-933 (2022-03-05)
Little evidence is available on oxalate balance in peritoneal dialysis (PD) patients. We performed a cross-sectional observational pilot study with 62 adult PD patients to document oxalate balance and explore its association with PD-related peritonitis. Plasma oxalate concentration, levels of
Natalia Stepanova et al.
Urolithiasis, 50(3), 249-258 (2022-02-08)
The present study aimed (i) to evaluate whether ceftriaxone treatment could affect not only intestinal oxalate-degrading bacteria number but also their total activity to degrade oxalate and influence oxalate homeostasis in rats, (ii) and to estimate the ability of commercially
Anna Kletzmayr et al.
Advanced science (Weinheim, Baden-Wurttemberg, Germany), 7(8), 1903337-1903337 (2020-04-25)
Calcium oxalate (CaOx) crystal-induced nephropathies comprise a range of kidney disorders, for which there are no efficient pharmacological treatments. Although CaOx crystallization inhibitors have been suggested as a therapeutic modality already decades ago, limited progress has been made in the

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