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O5632

Sigma-Aldrich

Linoleic acid, conjugated methyl ester

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Synonym(s):
CLA methyl ester, Octadecadienoic acid, conjugated, methyl ester
NACRES:
NA.25

biological source

plant (safflower)

Quality Level

assay

≥99% (GC)

form

liquid

technique(s)

GC/MS: suitable
HPLC: suitable

impurities

≤1% Linoleic acid methyl ester

functional group

carboxylic acid
ester

lipid type

omega FAs

shipped in

ambient

storage temp.

−20°C

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This Item
L1376L1012L6031
Linoleic acid ≥99%

L1376

Linoleic acid

Linoleic acid liquid, BioReagent, suitable for cell culture

L1012

Linoleic acid

technique(s)

GC/MS: suitable, HPLC: suitable

technique(s)

-

technique(s)

cell culture | mammalian: suitable

technique(s)

-

biological source

plant (safflower)

biological source

plant oil (safflower)

biological source

plant (Safflower oil)

biological source

synthetic (organic)

assay

≥99% (GC)

assay

≥99%

assay

≥99%

assay

≥98% (TLC)

form

liquid

form

liquid

form

liquid

form

liquid

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

Conjugated linoleic acid (CLA) describes the positional and geometric isomers of C18:2 fatty acids (FA) with a conjugated double bond. cis-9, trans-11 CLA are considered as the major isomers of CLA, based on in vitro experiments and animal studies in milk. The major source of CLA in human diet is the ruminant fat.

Application

Linoleic acid, conjugated methyl ester (CLA) has been used as a standard for the determination of isomers of CLA in milk samples by high performance liquid chromatography (HPLC), gas chromatography-mass spectrometry. It has also been used in the production of sn-1,3 diacyl glycerol.

Biochem/physiol Actions

Conjugated linoleic acid (CLA) isomers as supplements inhibit the growth of numerous human cancer cell lines. It also possesses immunostimulant properties, prevents diabetes and reduces atherosclerosis.

Other Notes

A mixture of cis- and trans-9,11- and -10,12-octadecadienoic acid methyl esters. Isomer ratio may vary from lot to lot.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves


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