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P6354

Sigma-Aldrich

1,2-Dioleoyl-sn-glycero-3-phosphocholine

lyophilized powder

Synonym(s):

PC, 1,2-Di(cis-9-octadecenoyl)-sn-glycero-3-phosphocholine, 3-sn-Phosphatidylcholine, 1,2-dioleoyl, L-α-Phosphatidylcholine, dioleoyl, L-β,γ-Dioleoyl-α-lecithin, DOPC

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About This Item

Empirical Formula (Hill Notation):
C44H84NO8P
CAS Number:
4235-95-4
Molecular Weight:
786.11
Beilstein/REAXYS Number:
3898070
EC Number:
224-193-8
MDL number:
MFCD00135191
UNSPSC Code:
51191904
PubChem Substance ID:
24898758
NACRES:
NA.25

biological source

synthetic (organic)

Quality Level

200

assay

≥99% (TLC)

form

lyophilized powder

functional group

phospholipid

lipid type

phosphoglycerides

shipped in

ambient

storage temp.

−20°C

SMILES string

[O-]P(OCC[N+](C)(C)C)(OC[C@]([H])(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O

InChI

1S/C44H84NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-34-36-43(46)50-40-42(41-52-54(48,49)51-39-38-45(3,4)5)53-44(47)37-35-33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h20-23,42H,6-19,24-41H2,1-5H3/b22-20-,23-21-/t42-/m1/s1

Inchi Key

SNKAWJBJQDLSFF-NVKMUCNASA-N

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Application

1,2-Dioleoyl-sn-glycero-3-phosphocholine has been used for the reconstitution of proteoliposome (PL). It has also been used in the preparation of lipid vesicles.

Packaging

Packaged under Argon

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Certificates of Analysis (COA)

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Lu Huang et al.
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Colloids and surfaces. B, Biointerfaces, 181, 837-844 (2019-06-30)
Liposomes are membrane models and excellent Drug Delivery Systems. However, their preparation is expensive, labor intensive, time consuming, and sometimes toxic. Recently, we published an innovative methodology for the production of homogeneous Small Unilamellar Vesicles (SUV) through a simple, fast
Hydrodynamic lift of vesicles under shear flow in microgravity
Callens N, et al.
EPL, 83(2), 24002-24002 (2008)
Arman Fathizadeh et al.
The journal of physical chemistry. B, 123(31), 6792-6798 (2019-07-16)
We investigate membrane permeation by the peptide WKW that is amidated at its C-terminus and therefore carries a positive charge of +2. To facilitate an efficient calculation, we introduce a novel set of simple coarse variables that measure permeation depth
Jessica J Hung et al.
Soft matter, 15(33), 6660-6676 (2019-08-08)
The dynamic behavior of monoclonal antibodies (mAbs) at high concentration provides insight into protein microstructure and protein-protein interactions (PPI) that influence solution viscosity and protein stability. At high concentration, interpretation of the collective-diffusion coefficient Dc, as determined by dynamic light
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