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Key Documents

PLA0061

Sigma-Aldrich

Rabbit anti-MCM3 Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

DNA polymerase alpha holoenzyme-associated protein P1, DNA replication factor MCM3, HCC5, MCM3 minichromosome maintenance deficient 3, MCM3 minichromosome maintenance deficient 3 (S. cerevisiae), P1-MCM3, P1.h, RLF subunit beta, RLFB, beta subunit, cervical cancer proto-oncogene 5, hRlf beta subunit, minichromosome maintenance deficient (S. cerevisiae) 3, minichromosome maintenance deficient 3, p102, replication licensing factor

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

species reactivity:
human
application:
IHC
IP
WB
technique(s):
immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:2,000- 1:10,000
citations:
2

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

grade

Powered by Bethyl Laboratories, Inc.

species reactivity

human

technique(s)

immunohistochemistry: 1:1,000-1:5,000
immunoprecipitation (IP): 2- 5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_002379.2

UniProt accession no.

shipped in

wet ice

Immunogen

The epitope recognized by PLA0061 maps to a region between residues 500 and 550 of human Minichromosome Maintenance 3 using the numbering given in entry NP_002379.2 (GeneID 4172).

Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide

Other Notes

The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM3 has been shown to interact with MCM5, CDC46, and the acetyltransferase MCM3AP.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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