RAB0734
Human SHBG / Sex Hormone-binding Globulin ELISA Kit
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UNSPSC Code:
41116158
NACRES:
NA.32
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species reactivity
human
packaging
kit of 96 wells (12 strips x 8 wells)
technique(s)
ELISA: suitable
input
sample type cell culture supernatant(s)
sample type plasma
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 1.2 pmol/L
standard curve range: 1.229-300 pmol/L
detection method
colorimetric
shipped in
wet ice
storage temp.
−20°C
Gene Information
human ... SHBG(6462)
Related Categories
General description
Serum sex hormone-binding globulin (SHBG) protein is a homodimer with a signal peptide and two laminin G-like domains. SHBG is produced by testis germ cells and released into the bloodstream by the liver. SHBG gene is located on human chromosome 17p13.1.
Application
Human SHBG/Sex Hormone-binding Globulin ELISA Kit has been used to measure serum sex hormone-binding globulin (SHBG) in whole blood samples. It has also been used to quantify SHBG in maternal peripheral and umbilical cord blood.
Biochem/physiol Actions
Serum sex hormone-binding globulin (SHBG) can bind and transport sex steroids and aid in modulating their biological active fraction. Direct action of SHBG modulates sex steroid actions in target cells. A low level of SHBG is detected in women with polycystic ovary syndrome (PCOS). The SHBG ELISA kit can be used for the quantitative measurement of sex hormone-binding globulin in cell culture supernatants, plasma and serum.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Met. Corr. 1
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
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1453723
Fortunati N and Catalano MG
Atlas of Genetics and Cytogenetics in Oncology and Haematology (2010)
Fangfang Wang et al.
EBioMedicine, 60, 102993-102993 (2020-09-20)
This study explored the mechanisms underlying altered neurobehavioural development of female offspring born to mothers with polycystic ovary syndrome (PCOS). In total, 20 women with PCOS and 32 healthy women who underwent caesarean deliveries with a single female foetus were
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