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Key Documents

SAB2103297

Sigma-Aldrich

Anti-ATP6V1C1, (N-terminal) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-ATP6C, Anti-ATP6D, Anti-FLJ20057, Anti-VATC, Anti-Vma5

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

42 kDa

species reactivity

dog, horse, human, mouse, bovine, rabbit, rat

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NM_001695

UniProt accession no.

P21283

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... ATP6V1C1(528)

General description

ATP6V1C1 (ATPase H+ transporting V1 subunit C1) is a subunit and regulator of V-ATPase (vacuolar ATPase).

Immunogen

Synthetic peptide directed towards the N terminal region of human ATP6V1C1

Biochem/physiol Actions

ATP6V1C1 (ATPase H+ transporting V1 subunit C1) is overexpressed in breast cancer, where it modulates the actin structure in a way that it promotes metastasis. This gene is up-regulated in oral squamous cell carcinoma (OSCC).

Sequence

Synthetic peptide located within the following region: ldafvegvvkkvaqymadvledskdkvqenllangvdlvtyitrfqwdma

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Atp6v1c1 may regulate filament actin arrangement in breast cancer cells.
Cai M et al
PLoS ONE, 9(1), e84833-e84833 (2014)
Immunohistochemical localization of C1 subunit of V-ATPase (ATPase C1) in oral squamous cell cancer and normal oral mucosa.
Garcia-Garcia A et al
Biotechnic & Histochemistry, 87(2), 133-139 (2012)

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