SAB4300276

Anti-phospho-PXN (pTyr⁸⁸) antibody produced in rabbit

affinity isolated antibody

• Synonym(s): Anti-FLJ16691 antibody produced in rabbit, Anti-paxillin antibody produced in rabbit
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: ~68 kDa
• species reactivity: human
• concentration: 1 mg/mL
• technique(s): indirect immunofluorescence: 1:100-1:200; western blot: 1:500-1:1000
• isotype: IgG
• immunogen sequence: (P-V-YP-G-S)
• NCBI accession no.: NP_001074324.1
• UniProt accession no.: P49023
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pTyr88)
• Gene Information: human ... PXN(5829)

Description

Immunogen

Peptide sequence around phosphorylation site of tyrosine 88 (P-V-Y(p)-G-S), according to the protein PXN.

Features and Benefits

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Target description

An antiphosphotyrosine antibody was used to identify proteins that are phosphorylated in Rous sarcoma virus-transformed chick embryo fibroblasts, and a 76-kD protein was obtained that localizes to focal adhesions at the ends of actin-containing stress fibers in nontransformed cells (Ref.1). This protein was purified from chicken gizzard smooth muscle, and was named Pxn (Paxillin) ('paxillus' means 'small stake' or 'peg' in Latin) as a protein tethered to the membrane at focal adhesions

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable