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SAB4502603

Sigma-Aldrich

Anti-CYCLIN D1 antibody produced in rabbit

affinity isolated antibody

Synonym(s):

BCL-1 oncogene, BCL1, CYL-1, G1/S-specific cyclin D1, cyclin D1

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About This Item

MDL number:
MFCD00239664
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 33 kDa

species reactivity

human, rat, mouse

concentration

~1 mg/mL

technique(s)

ELISA: 1:5000
western blot: 1:500-1:1000

NCBI accession no.

P24385

UniProt accession no.

P24385

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... CCND1(595)

General description

Anti-CYCLIN D1 Antibody detects endogenous levels of total CYCLIN D1 protein.

Immunogen

The antiserum was produced against synthesized peptide derived from human Cyclin D1.

Immunogen Range: 56-105

Application

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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Adrian Krajewski et al.
Cancer management and research, 12, 13085-13097 (2020-12-31)
Cyclins are well-known cell cycle regulators. The activation of cyclin-dependent kinases by cyclins allows orchestration of the complicated cell cycle machinery and drives the cell from the G1 phase to the end of the mitotic phase. In recent years, it
Chao Tian et al.
OncoTargets and therapy, 13, 5353-5361 (2020-07-02)
MCTS1 re-initiation and release factor (MCTS1) is a ribosome-binding protein and shows multiple oncogenic properties in multiple cancers. This study aimed to investigate the expression, prognostic significance and transcription profile of MCTS1 in the PAM50 subtypes of breast cancer, as
Yü Liu et al.
Molecular medicine reports, 20(1), 125-134 (2019-05-23)
Interleukin enhancer‑binding factor 3 (ILF3) may function as a transcriptional coactivator and has been reported to be involved in tumor proliferation and metastasis; however, its role and clinical value in gastric cancer (GC) remains unclear. To understand the value of
Huaming Wei et al.
OncoTargets and therapy, 13, 13401-13411 (2021-01-08)
To investigate the effect of TRIM47 on glioma cells and further explore its underlying molecular mechanisms. Mouse xenograft model was used in this study. The mRNA expression of TRIM47 was detected by qRT-PCR. The cell viability and proliferation activity was
Xiangtai Wei et al.
Technology in cancer research & treatment, 13(1), 87-93 (2013-07-26)
Rhomboid domain containing 1 (RHBDD1) gene, a new member of rhomboid family of proteins is highly responsible for the regulation of apoptosis by cleaving pro-apoptotic Bcl-2 family protein BIK. Therefore, the higher expression levels of RHBDD1 in cancer tissues may
View All Related Papers

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