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SAB4502982

Sigma-Aldrich

Anti-TNFA antibody produced in rabbit

affinity isolated antibody

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Synonym(s):
Cachectin, TNF-α, TNF-a, Tumor necrosis factor, Tumor necrosis factor ligand superfamily member 2
MDL number:
NACRES:
NA.41

biological source

rabbit

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 25 kDa

species reactivity

mouse, human, rat

concentration

~1 mg/mL

technique(s)

ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100

NCBI accession no.

UniProt accession no.

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... TNF(7124)

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This Item
SAB5700627SAB5700698WH0007124M2
Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

purified immunoglobulin

conjugate

unconjugated

conjugate

-

conjugate

-

conjugate

unconjugated

shipped in

wet ice

shipped in

wet ice

shipped in

wet ice

shipped in

dry ice

technique(s)

ELISA: 1:10000, immunohistochemistry: 1:50-1:100, immunofluorescence: 1:100-1:500

technique(s)

immunofluorescence: 1:50-1:200, immunohistochemistry: 1:50-1:200, western blot: 1:1000-1:2000

technique(s)

immunofluorescence: 1:50-1:100, immunohistochemistry: 1:50-1:100, western blot: 1:1000-1:2000

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

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General description

Anti-TNFA Antibody detects endogenous levels of total TNFA protein.
The TNFA (tumor necrosis factor α) gene is mapped to human chromosome 6p21.33 and codes for a pro-inflammatory cytokine.

Immunogen

The antiserum was produced against synthesized peptide derived from human TNFA.

Immunogen Range: 141-190

Biochem/physiol Actions

The TNFA (tumor necrosis factor α) gene is significantly associated with the regulation of innate and adaptive immune responses. Polymorphism of TNFA gene is known to cause acute motor axonal neuropathy. The cytokine release and gene action is associated with epithelial cells, myeloid cells, endothelial, as well as tumor cells. Tumor cells are known to release TNFA, specifically in response to chemotherapy

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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