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SAB5500098

Sigma-Aldrich

Anti-EGFR antibody, Rabbit monoclonal

clone SP111, recombinant, expressed in proprietary host, affinity isolated antibody

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NACRES:
NA.41

biological source

rabbit

Quality Level

recombinant

expressed in proprietary host

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

SP111, monoclonal

species reactivity

human (tested)

technique(s)

immunoblotting: 1:300
immunohistochemistry: 1:100

isotype

IgG

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

target post-translational modification

unmodified

Gene Information

human ... EGFR(1956)

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SAB5500099SAB5700051SAB5700347
biological source

rabbit

biological source

rabbit

biological source

rabbit

biological source

rabbit

species reactivity

human (tested)

species reactivity

human (tested)

species reactivity

human, rat, mouse

species reactivity

mouse, human

Gene Information

human ... EGFR(1956)

Gene Information

human ... EGFR(1956)

Gene Information

human ... EGFR(1956)

Gene Information

human ... EGFR(1956)

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

conjugate

-

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

antibody form

affinity isolated antibody

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General description

EGFR is a transmembrane tyrosine kinase that belongs to the HER/erbB protein family. Somatic mutations in the tyrosine kinase domain of EGFR are present in a subset of lung adenocarcinoma. Two types of mutations account for approximately 90% of mutant cases: a specific point mutation L858R which occurs in exon 21 and short in-frame deletions in exon 19. A common lesion in exon 19 is the deletion of E746-A750, although other variants can also occur.

Immunogen

E746-A750del specific

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

0.1 ml rabbit monoclonal antibody purified by protein A/G in PBS/1% BSA buffer pH 7.6 with less than 0.1% sodium azide.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Storage Class

10 - Combustible liquids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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