SAB5702375

Anti-GATA4 Antibody, clone 1M2E4, Rabbit Monoclonal

• Synonym(s): ASD2, TACHD, TOF, VSD1
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 1M2E4, monoclonal
• form: liquid
• mol wt: 55 kDa
• species reactivity: human, rat, rat
• concentration: 0.5 mg/mL
• technique(s): immunohistochemistry: 1:100 - 1:500; western blot: 1:500 - 1:1000
• color: colorless
• isotype: IgG
• immunogen sequence: ASGASSNSSNATTSSSEEMRPIKTEPGLSSHYGHSSSVSQTFSVSAMSGHGPSIHPVLSALKLSPQGYASPVSQSPQTSSKQDSWNSLVLADSHGDIITA
• UniProt accession no.: P43694
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... GATA4(2626)

Description

General description

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 343-442 of human GATA4 (NP_002043.2).

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IHC

Safety Information

• pictograms: GHS07,GHS09
• signalword: Warning
• hcodes: H317,H411
• pcodes: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• Hazard Classifications: Aquatic Chronic 2 - Skin Sens. 1
• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3