SAB5702690
Anti-DHFR Antibody, clone 7N3X4, Rabbit Monoclonal
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Synonym(s):
DHFRP1, DYR
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
material
colorless
clone
7N3X4, monoclonal
form
liquid
mol wt
20 kDa
species reactivity
human, rat, rat
concentration
0.35 mg/mL
technique(s)
western blot: 1:500 - 1:2000
color
colorless
isotype
IgG
immunogen sequence
HFLSRSLDDALKLTEQPELANKVDMVWIVGGSSVYKEAMNHPGHLKLFVTRIMQDFESDTFFPEIDLEKYKLLPEYPGVLSDVQEEKGIKYKFEVYEKND
UniProt accession no.
shipped in
wet ice
storage temp.
−20°C
target post-translational modification
unmodified
Gene Information
human ... DHFR(1719)
General description
Dihydrofolate reductase converts dihydrofolate into tetrahydrofolate, a methyl group shuttle required for the de novo synthesis of purines, thymidylic acid, and certain amino acids. While the functional dihydrofolate reductase gene has been mapped to chromosome 5, multiple intronless processed pseudogenes or dihydrofolate reductase-like genes have been identified on separate chromosomes. Dihydrofolate reductase deficiency has been linked to megaloblastic anemia. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2014]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 88-187 of human DHFR (P00374).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB
wgk_germany
WGK 1
Certificates of Analysis (COA)
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