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SMB00079

Sigma-Aldrich

Ricinine

≥95% (LC/MS-ELSD)

Synonym(s):

Recinine, Ricidine, Ricinin, Ritsinin

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About This Item

Empirical Formula (Hill Notation):
C8H8N2O2
CAS Number:
524-40-3
Molecular Weight:
164.16
MDL number:
MFCD00171320
UNSPSC Code:
12352205
PubChem Substance ID:
329824757
NACRES:
NA.25

assay

≥95% (LC/MS-ELSD)

form

solid

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

COC1=C(C#N)C(=O)N(C)C=C1

InChI

1S/C8H8N2O2/c1-10-4-3-7(12-2)6(5-9)8(10)11/h3-4H,1-2H3

InChI key

PETSAYFQSGAEQY-UHFFFAOYSA-N

General description

Ricinine is an alkaloidal toxin primarily sourced from castor beans (Ricinus communis). It belongs to the piperidine alkaloids group and contains a cyano group in its structure that contributes to its toxicity.

Biochem/physiol Actions

Dueto its toxicity, ricinine possesses insecticidal, antibacterial, and antifungalproperties against many species. It serves as a preliminary biomarker for therapid detection of ricin in blood and urine samples.

pictograms

Skull and crossbones
GHS06

signalword

Danger

hcodes

H301

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
1222282478
122228478V
122228469V
122228213V
122228-213V

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Xin Wen et al.
Journal of proteomics, 201, 27-36 (2019-04-08)
Low temperatures profoundly influence the physiological and behavioural processes of ectotherms, especially teleosts, which have made them the subjects of strong interest over time. However, the characteristics of fish cold-tolerance at the protein level remain unclear. Therefore, to shed further
Munmi Majumder et al.
Scientific reports, 9(1), 14493-14493 (2019-10-12)
Medicinal plant-based therapies can be important for treatment of cancer owing to high efficiency, low cost and minimal side effects. Here, we report the anti-cancer efficacy of Ricinus communis L. fruit extract (RCFE) using estrogen positive MCF-7 and highly aggressive
Artem Blagodatski et al.
Cells, 9(3) (2020-03-07)
The Wnt signaling is one of the major pathways known to regulate embryonic development, tissue renewal and regeneration in multicellular organisms. Dysregulations of the pathway are a common cause of several types of cancer and other diseases, such as osteoporosis
Nick Verougstraete et al.
Journal of analytical toxicology, 43(3), e1-e5 (2018-12-28)
Ricin is a highly toxic agent derived from the castor bean plant (Ricinus communis). Poisoning occurs commonly by oral ingestion of the beans. Injection of ricin is believed to be more lethal. Ricin is a large glycosylated protein difficult to
Rudolph C Johnson et al.
Journal of analytical toxicology, 29(3), 149-155 (2005-04-22)
Ricin is a toxalbumin derived from the castor bean plant, Ricinus communis. Ricinine is an alkaloid (3-cyano-4-methoxy-N-methyl-2-pyridone) that shares a common plant source with ricin, and its presence in urine infers ricin exposure. A new quantification method for ricinine was
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