SMB00502

Fangchinoline

≥98% (HPLC)

• Synonym(s): (+)-Limacine, 7-O-Demethyltetrandine, Frangchinoline, Limacine
• Empirical Formula (Hill Notation): C₃₇H₄₀N₂O₆
• CAS Number: 436-77-1
• Molecular Weight: 608.72
• MDL number: MFCD03427706
• UNSPSC Code: 12352205
• PubChem Substance ID: 329825029
• NACRES: NA.25

Properties

• assay: ≥98% (HPLC)
• form: powder
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: 2-8°C
• SMILES string: CN([C@@]1([H])CC(C=C2)=CC=C2OC3=C(OC)C=CC4=C3)CCC5=C1C=C(OC6=C([C@@](C4)([H])N(C)CC7)C7=CC(OC)=C6O)C(OC)=C5
• InChI: 1S/C37H40N2O6/c1-38-14-12-24-19-31(42-4)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-32-18-23(8-11-30(32)41-3)17-29-35-25(13-15-39(29)2)20-34(43-5)36(40)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3/t28-,29-/m0/s1
• InChI key: IIQSJHUEZBTSAT-VMPREFPWSA-N

Description

General description

A bisbenzylisoquinoline alkaloid found in Stephania tetrandra.

Biochem/physiol Actions

Fangchinoline is a phytochemical that has been shown to elicit anti-cancer effects in prostate and breast cancer cell lines via inducing G1 cell cycle arrest. It has also been shown to inhibit cell proliferation and cell cycle progression in rat aortic vascular smooth muscle cells.

Safety Information

• pictograms: GHS07
• signalword: Warning
• hcodes: H302
• pcodes: P301 + P312 + P330
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable