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SML0530

Sigma-Aldrich

Clonixin

≥98% (HPLC)

Synonym(s):

2-[(3-Chloro-2-methylphenyl)amino]-3-pyridinecarboxylic acid, CBA 93626, Chlonixin, Clonixic acid, Clonixin, Clonixine, NSC 335505, Sch 10304

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About This Item

Empirical Formula (Hill Notation):
C13H11ClN2O2
CAS Number:
17737-65-4
Molecular Weight:
262.69
MDL number:
MFCD00864292
UNSPSC Code:
12352200
PubChem Substance ID:
329825534
NACRES:
NA.77

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 15 mg/mL, clear

storage temp.

room temp

SMILES string

Cc1c(Cl)cccc1Nc2ncccc2C(O)=O

InChI

1S/C13H11ClN2O2/c1-8-10(14)5-2-6-11(8)16-12-9(13(17)18)4-3-7-15-12/h2-7H,1H3,(H,15,16)(H,17,18)

InChI key

CLOMYZFHNHFSIQ-UHFFFAOYSA-N

Biochem/physiol Actions

Clonixin is a non steroidal anti inflammatory drug (NSAID) with analgesic properties. The compound has been reported to block prostaglandin synthesis, and to block inward calcium currents.

pictograms

Exclamation mark
GHS07

signalword

Warning

hcodes

H302

Hazard Classifications

Acute Tox. 4 Oral

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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L W Kissell et al.
Journal of dairy science, 95(12), 7151-7157 (2012-10-09)
The objective of this study was to determine if the plasma pharmacokinetics and milk elimination of flunixin (FLU) and 5-hydroxy flunixin (5OH) differ following intramuscular and subcutaneous injection of FLU compared with intravenous injection. Twelve lactating Holstein cows were used
D Goerigk et al.
Tierarztliche Praxis. Ausgabe G, Grosstiere/Nutztiere, 40(2), 112-118 (2012-04-25)
Malignant catarrhal fever (MCF) is a worldwide occurring sporadic disease of cloven-hoofed animals. For the first time, this case report describes clinical and pathological as well as histopathological findings in an alpaca suffering from MCF caused by ovine herpesvirus 2.
David Douglas et al.
Journal of food protection, 75(7), 1270-1277 (2012-09-18)
β-Lactam antibiotics are the most commonly used drugs on dairy farms. β-Lactam residues in milk are kept out of the human milk supply with good agricultural practices and mandatory truck screening performed by the dairy industry under Appendix N of
Jeffrey M B Musser et al.
Journal of the American Veterinary Medical Association, 242(2), 205-208 (2013-01-02)
To investigate the disposition kinetics of flunixin meglumine when administered IV to budgerigars (Melopsittacus undulatus) and Patagonian conures (Cyanoliseus patagonus). Prospective cohort study. 8 adult Patagonian conures and 24 adult budgerigars. Injectable flunixin meglumine (50 mg/mL) was diluted to 10
J H Foreman et al.
Equine veterinary journal. Supplement, (43)(43), 17-20 (2013-03-02)
There are no refereed controlled documentations of the skeletal analgesic efficacy of different dosages of flunixin meglumine (FM). The objective of this experiment was to compare the efficacy of various dosages of FM with a negative control. The hypothesis was
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