SML1062

6-Aminophenanthridine

≥98% (HPLC)

• Synonym(s): 6-Amino-phenanthridine, 6AP
• Empirical Formula (Hill Notation): C₁₃H₁₀N₂
• CAS Number: 832-68-8
• Molecular Weight: 194.23
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥98% (HPLC)
• form: powder
• color: white to brown
• solubility: DMSO: 20 mg/mL, clear
• storage temp.: 2-8°C
• InChI: 1S/C13H10N2/c14-13-11-7-2-1-5-9(11)10-6-3-4-8-12(10)15-13/h1-8H,(H2,14,15)
• InChI key: FVCXJXKLDUJOFA-UHFFFAOYSA-N

Description

Biochem/physiol Actions

6-Aminophenanthridine selectively inhibits protein folding activity of the ribosome (PFAR). Apparently 6-Aminophenanthridine interacts with the ribosome domain V rRNA and the protein substrate. 6-Aminophenanthridine is an antiprion compound that promotes mammalian prion clearance.

Features and Benefits

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Safety Information

• pictograms: GHS06
• signalword: Danger
• hcodes: H301,H319
• pcodes: P301 + P310 + P330 - P305 + P351 + P338
• Hazard Classifications: Acute Tox. 3 Oral - Eye Irrit. 2
• Storage Class: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable