SML3309
DN01
≥98% (HPLC)
Synonym(s):
4-(4-((Dimethylamino)methyl)-2,6-dimethoxyphenyl)-7-fluoro-2-methylisoquinolin-1(2H)-one
Sign Into View Organizational & Contract Pricing
All Photos(1)
About This Item
Empirical Formula (Hill Notation):
C21H23FN2O3
CAS Number:
Molecular Weight:
370.42
UNSPSC Code:
12352200
NACRES:
NA.77
Recommended Products
Quality Level
assay
≥98% (HPLC)
form
powder
color
, White to light brown
solubility
DMSO: 2 mg/mL, clear
storage temp.
-10 to -25°C
Biochem/physiol Actions
DN01 is a potent and selective BRD8 first bromodomain inhibitor (BRD8(1) IC50 = 12 nM; BRD4(1) & BRD9 IC50 ≥10 μM) that serves as a useful chemical probe for the selective engagement of BRD8 and enrichment of native NuA4 complexes.
Storage Class
11 - Combustible Solids
wgk_germany
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Choose from one of the most recent versions:
Certificates of Analysis (COA)
Lot/Batch Number
Don't see the Right Version?
If you require a particular version, you can look up a specific certificate by the Lot or Batch number.
Already Own This Product?
Find documentation for the products that you have recently purchased in the Document Library.
Chemoproteomics Enabled Discovery of Selective Probes for NuA4 Factor BRD8
ACS Chemical Biology, 16(11):, 2185-2192 (2021)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Contact Technical Service