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MilliporeSigma

SML3821

Sigma-Aldrich

CAS-12290-201

≥98% (HPLC)

Synonym(s):

3-((1-(2-chloroacetyl)azetidin-3-yl)methyl)-7-fluoroquinazolin-4(3H)-one

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About This Item

Empirical Formula (Hill Notation):
C14H13ClFN3O2
Molecular Weight:
309.72
UNSPSC Code:
12352200
NACRES:
NA.21
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Quality Level

assay

≥98% (HPLC)

form

powder

color

white to beige

solubility

DMSO: 2 mg/mL, clear (Warmed)

storage temp.

2-8°C

Biochem/physiol Actions

CAS-12290-201, a fluoroquinazolinone compound, is cell penetrant, selective and potent chemical probe for deubiquitinating enzymes (DUB) VCPIP1. CAS-12290-201 covalently labels the catalytic cysteine of VCPIP1.
Cell penetrant, selective and potent chemical probe for deubiquitinating enzymes (DUB) VCPIP1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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Accelerating inhibitor discovery for deubiquitinating enzymes
Nature Communications, 14(1), 686-686 (2023)

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