Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

SRP0436

Sigma-Aldrich

PDE7A active rat

recombinant, expressed in baculovirus infected Sf9 cells, ≥30% (SDS-PAGE)

Synonym(s):

phosphodiesterase 7A

Sign Into View Organizational & Contract Pricing

Select a Size

10 μG
$568.00

$568.00


Availability
Usually ships in 2 weeks.

Request a Bulk Order

Select a Size

Change View
10 μG
$568.00

About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

$568.00


Availability
Usually ships in 2 weeks.

Request a Bulk Order

biological source

rat

recombinant

expressed in baculovirus infected Sf9 cells

assay

≥30% (SDS-PAGE)

form

aqueous solution

mol wt

65 kDa

packaging

pkg of 10 μg

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
SRP0437SRP0434SRP0435
biological source

rat

biological source

rat

biological source

mouse

biological source

mouse

Gene Information

rat ... PDE7A(81744)

Gene Information

rat ... PDE7B(140929)

Gene Information

mouse ... PDE7A(18583)

Gene Information

mouse ... PDE7B(29863)

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

recombinant

expressed in baculovirus infected Sf9 cells

form

aqueous solution

form

aqueous solution

form

aqueous solution

form

aqueous solution

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

General description

Rat PDE7A (GenBank Accession No. NM_031080) amino acids 147-482 (end) with N-terminal GST-tag, MW=65 kDa, expressed in a Baculovirus-infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

Need A Sample COA?

This is a sample Certificate of Analysis (COA) and may not represent a recently manufactured lot of this specific product.

Already Own This Product?

Find documentation for the products that you have recently purchased in the Document Library.

Visit the Document Library

Satoshi Yamamoto et al.
European journal of pharmacology, 541(1-2), 106-114 (2006-06-20)
YM-393059, (+/-)-N-(4,6-dimethylpyrimidin-2-yl)-4-[2-(4-methoxy-3-methylphenyl)-5-(4-methylpiperazin-1-yl)-4,5,6,7-tetrahydro-1H-indol-1-yl]benzenesulfonamide difumarate, is a novel phosphodiesterase (PDE) inhibitor that inhibited the PDE7A isoenzyme with a high potency (IC50=14 nM) and PDE4 with a moderate potency (IC50=630 nM). In a cell-based assay, YM-393059 was found to inhibit anti-CD3 antibody, Staphylococcal
Guchen Yang et al.
Journal of immunology (Baltimore, Md. : 1950), 171(12), 6414-6420 (2003-12-10)
Phosphodiesterases (PDEs) are enzymes which hydrolyze the cyclic nucleotide second messengers, cAMP and cGMP. In leukocytes, PDEs are responsible for depletion of cAMP which broadly suppresses cell functions and cellular responses to many activation stimuli. PDE7A has been proposed to
Assignment of the mouse Pde7A gene to the proximal region of chromosome 3 and of the human PDE7A gene to chromosome 8q13.
P Han et al.
Genomics, 48(2), 275-276 (1998-04-02)

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Contact Technical Service