SRP6163

FLT-3 Ligand human

recombinant, expressed in HEK 293 cells, ≥95% (SDS-PAGE)

• Synonym(s): CD135, FLK2, Fms-related tyrosine kinase 3 ligand, STK1, Stem cell tyrosine kinase 1
• UNSPSC Code: 12352200
• NACRES: NA.32

Properties

• biological source: human
• recombinant: expressed in HEK 293 cells
• assay: ≥95% (SDS-PAGE)
• form: lyophilized
• mol wt: 24-30 kDa (monomer, glycosylated)
• packaging: pkg of 10 μg
• technique(s): cell culture | mammalian: suitable
• NCBI accession no.: P36888
• UniProt accession no.: P36888
• shipped in: dry ice
• Storage temp.: −70°C
• Gene Information: human ... FLT3(2322)

Description

General description

FLT3 ligand is a receptor for the Flt3 cytokine and has a tyrosine-protein kinase activity & a growth factor that regulates proliferation of early hematopoietic cells. Flt3-Ligand synergizes with other CSFs and interleukins to induce growth and differentiation. Human flt3-Ligand (flk2-ligand) stimulates the proliferation and colony formation of certain bone marrow precursor cells including CD34+ cells.

Physical form

Lyophilized from a PBS solution.

Preparation Note

Centrifuge the vial prior to opening.

Reconstitution

Reconstitute in sterile PBS containing 0.1% endotoxin-free, recombinant human serum albumin.

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable