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Z740270

Aluminum heating/cooling block

Holds 96 x 0.2 mL tubes in center plus 10 on size (4 for 1.5ml tubes, 6 for 0.5ml tubes)

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Synonym(s):
dry block, tube cooling block, tube heating block
UNSPSC Code:
41102404
NACRES:
NB.35

material

aluminum

feature

Holds 96 x 0.2 mL tubes in center plus 10 on size (4 for 1.5ml tubes, 6 for 0.5ml tubes)

packaging

pkg of 1 ea

manufacturer/tradename

Diversified Biotech CHAM-1000

technique(s)

PCR: suitable

size

156x76x25 mm

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General description

Each Cooling Chamber is a solid aluminum block that surrounds inserted tubes to guarantee sustained hot or cold temperatures.

Application

Aluminum heating/cooling block has been used to cool PCR tubes during dilution of DNA fragments and the preparation of the enzyme master mix for in vitro cyclic GMP-AMP synthase (cGAS)reaction.

Certificates of Analysis (COA)

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Andreas Holleufer et al.
Bio-protocol, 8(20), e3055-e3055 (2018-10-20)
Cyclic GMP-AMP synthase (cGAS) is a pattern recognition receptor (PRR) that senses double stranded DNA (dsDNA) in the cytosol and this leads to the activation of stimulator of interferon genes (STING) via the secondary messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP). STING then

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