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53210-U

Supelco

SupelMIP® SPE - Chloramphenicol

bed wt. 25 mg, volume 10 mL , LRC, pk of 50

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NACRES:
NB.21

material

polypropylene tube

Quality Level

product line

SupelMIP®

composition

bed wt., 25 mg

packaging

pk of 50

technique(s)

solid phase extraction (SPE): suitable

volume

10 mL , LRC

application(s)

food and beverages

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SupelMIP® SPE - Patulin

composition

bed wt., 25 mg

composition

bed wt., 25 mg

composition

bed wt., 50 mg

composition

bed wt, 100 mg

packaging

pk of 50

packaging

pk of 50

packaging

pk of 50

packaging

pk of 50 ea

volume

10 mL , LRC

volume

3 mL

volume

3 mL

volume

3 mL

application(s)

food and beverages

application(s)

food and beverages

application(s)

-

application(s)

food and beverages

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

General description

SupelMIP SPE phases were developed by MIP Technologies AB, which is one of the leading authorities and commercial pioneers of molecular imprinted polymers for process scale separations, analytical chromatography, and sample preparation.

The SupelMIP SPE line consist s of highly cross-linked polymers that are engineered to extract a single analyte of interest or a class of structurally related analytes with an extremely high degree of selectivity. This is possible because selectivity is introduced during MIP synthesis in which a template molecule, designed to mimic the analyte, guides the formation of specific cavities or imprints that are sterically and chemically complementary to the analyte(s) of interest.

By careful design of the imprinting site, either by molecular modeling, experimental design, or screening methods, the binding cavities can be engineered to offer multiple interaction points with the analyte(s) of interest. This leads to a stronger interaction between the solid-phase and the analyte(s). As a consequence, harsher wash conditions can be tolerated during SPE methodology resulting in cleaner extracts. Because extraction selectivity is significantly improved, lower background is observed allowing analysts to achieve lower limits of detection.

Visit www.sigma-aldrich.com/supelmip to learn more.

Application

A MIP phase developed and optimized for the selective extraction of chloramphenicol in biological matrices.

Chloramphenicol is a broad-spectrum antibiotic that is currently banned by a number of countries including the EU, the US, and Canada. This MIP phase and associated method offer a simple, efficient, and highly selective extraction method for quantiting chloramphenicol in food products and biological matrices. Detection limits well below the minim required performance limit (MPRL) are achieved consistently.

Features and Benefits

  • Highly selective SPE for trace analysis in complex matrices
  • Achieve lower detection limits
  • Significant time and cost savings
  • Improved MS-compatibility

Legal Information

SupelMIP is a registered trademark of Sigma-Aldrich Co. LLC

Signal Word

Danger

Hazard Statements

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 2 - Eye Dam. 1 - STOT SE 3

Target Organs

Respiratory system

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

200.3 °F

Flash Point(C)

93.5 °C


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Related Content

SupelMIP Molecularly Imprinted Polymer SPE Cartridges

SupelMIP SPE is based on molecularly imprinted polymer (MIP) technology. Each SupelMIP phase offers tailor-made selectivity for the extraction of trace analytes in complex matrixes.

Chromatograms

application for SPE, application for LC-MS

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

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