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1046205

USP

Aztreonam

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

[2S-[2α,3β(Z)]]-2-[[[1-(2-Amino-4-thiazolyl)-2-[(2-methyl-4-oxo-1-sulfo-3-azetidinyl)amino]-2-oxoethylidene]amino]oxy]-2-methylpropanoic acid

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About This Item

Empirical Formula (Hill Notation):
C13H17N5O8S2
CAS Number:
Molecular Weight:
435.43
MDL number:
UNSPSC Code:
41116107
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

aztreonam

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

storage temp.

−20°C

SMILES string

C[C@H]1[C@H](NC(=O)\C(=N/OC(C)(C)C(O)=O)c2csc(N)n2)C(=O)N1S(O)(=O)=O

InChI

1S/C13H17N5O8S2/c1-5-7(10(20)18(5)28(23,24)25)16-9(19)8(6-4-27-12(14)15-6)17-26-13(2,3)11(21)22/h4-5,7H,1-3H3,(H2,14,15)(H,16,19)(H,21,22)(H,23,24,25)/b17-8-/t5-,7-/m0/s1

InChI key

WZPBZJONDBGPKJ-VEHQQRBSSA-N

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General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Aztreonam USP reference standard is meant to use for specified quality tests and assays.

Also used to prepare standard and system suitability solutions for assay according to the given below monographs of United States Pharmacopeia (USP):
  • Aztreonam
  • Aztreonam for Injection
  • Aztreonam Injection

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 2

flash_point_f

Not applicable

flash_point_c

Not applicable


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Aztreonam
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 43(2), 460-460 (2020)
Aztreonam for Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 463-463 (2018)
D H Johnson et al.
The Medical clinics of North America, 79(4), 733-743 (1995-07-01)
Aztreonam is a monocyclic beta-lactam antibiotic that is active exclusively against the aerobic gram-negative bacilli. It is not ototoxic or nephrotoxic and so is used as an alternative to aminoglycosides in a variety of clinical situations. In polymicrobial infections or
Aztreonam Injection
United States Pharmacopeia and National Formulary
United States Pharmacopeia, 39(3), 462-462 (2018)
W C Hellinger et al.
Mayo Clinic proceedings, 74(4), 420-434 (1999-04-30)
Imipenem and meropenem, members of the carbapenem class of beta-lactam antibiotics, are among the most broadly active antibiotics available for systemic use in humans. They are active against streptococci, methicillin-sensitive staphylococci, Neisseria, Haemophilus, anaerobes, and the common aerobic gram-negative nosocomial

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