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1056504

USP

1,4-Benzoquinone

United States Pharmacopeia (USP) Reference Standard

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Synonym(s):
p-Benzoquinone, ,5-Cyclohexadiene-1,4-dione, Quinone
Linear Formula:
C6H4(=O)2
CAS Number:
Molecular Weight:
108.09
Beilstein/REAXYS Number:
773967
MDL number:
PubChem Substance ID:
NACRES:
NA.24

grade

pharmaceutical primary standard

vapor density

3.73 (vs air)

vapor pressure

0.1 mmHg ( 25 °C)

autoignition temp.

815 °F

manufacturer/tradename

USP

mp

113-115 °C (lit.)

application(s)

pharmaceutical (small molecule)

format

neat

SMILES string

O=C1C=CC(=O)C=C1

InChI

1S/C6H4O2/c7-5-1-2-6(8)4-3-5/h1-4H

InChI key

AZQWKYJCGOJGHM-UHFFFAOYSA-N

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1 of 4

This Item
PHR102815970051066009
1,4-Benzoquinone United States Pharmacopeia (USP) Reference Standard

1056504

1,4-Benzoquinone

1,4-Benzoquinone Pharmaceutical Secondary Standard; Certified Reference Material

PHR1028

1,4-Benzoquinone

Quinine sulfate United States Pharmacopeia (USP) Reference Standard

1597005

Quinine sulfate

Betamethasone United States Pharmacopeia (USP) Reference Standard

1066009

Betamethasone

manufacturer/tradename

USP

manufacturer/tradename

-

manufacturer/tradename

USP

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

application(s)

pharmaceutical (small molecule)

format

neat

format

neat

format

neat

format

neat

vapor density

3.73 (vs air)

vapor density

3.73 (vs air)

vapor density

-

vapor density

-

vapor pressure

0.1 mmHg ( 25 °C)

vapor pressure

0.1 mmHg ( 25 °C)

vapor pressure

-

vapor pressure

<0.0000001 kPa ( 25 °C)

General description

1,4-Benzoquinone, also known as para-quinone, is a benzene derivative with cyclic dienedione structure.

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets, have been developed and issued under the Authority of the issuing Pharmacopoeia.

1,4-Benzoquinone is a dark yellow powder having a green cast. It is slightly soluble in water and soluble in alcohol, in ether, and in fixed alkali solutions. It may darken on standing.

Application

The USP pharmaceutical reference standard is intended for use in analytical or laboratory applications as specified in USP compendia.

Also ideal for use as a primary reference standard in the following tests or assays according to USP General Chapter <11>:

  • pure steam
  • water for injection
  • sterile water for inhalation
  • sterile water for injection
  • sterile water for irrigation
  • purified water
  • sterile purified water
  • water for hemodialysis
  • <643>total organic carbon

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Related product

signalword

Danger

Hazard Classifications

Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Flam. Sol. 1 - Muta. 2 - Skin Corr. 1B - Skin Sens. 1 - STOT SE 3

target_organs

Respiratory system

Storage Class

4.1B - Flammable solid hazardous materials

wgk_germany

WGK 3

flash_point_f

170.6 °F - closed cup

flash_point_c

77 °C - closed cup


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Total organic carbon
United States Pharmacopeia/National Formulary, 45(6), 6867-6867 (2021)
Electrochemical detoxification of a 1, 4-benzoquinone solution in wastewater treatment.
Pulgarin, Cesar, et al.
Water Research, 28.4, 887-893 (1994)
Aromatic alcohols and carbonyl compounds
Smith PWG and Tatchell AR
Aromatic Chemistry (2016)
1,4-Benzoquinone
United States Pharmacopeia/National Formulary, 6079-6079 (2013)
Rajaram Venkatesan et al.
Nature communications, 5, 4805-4805 (2014-09-10)
Mitochondrial fatty acid synthesis (mtFAS) is essential for respiratory growth in yeast and mammalian embryonic survival. The human 3-ketoacyl-acyl carrier protein (ACP) reductase (KAR) of mtFAS is a heterotetrameric α2β2-assembly composed of 17β-hydroxysteroid dehydrogenase type-8 (HSD17B8, α-subunit) and carbonyl reductase

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