1096622

Carvedilol

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol, BM-14190
• Empirical Formula (Hill Notation): C₂₄H₂₆N₂O₄
• CAS Number: 72956-09-3
• Molecular Weight: 406.47
• MDL number: MFCD00864692
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749239
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• API family: carvedilol
• manufacturer/tradename: USP
• application(s): pharmaceutical (small molecule)
• format: neat
• SMILES string: OC(COC1=CC=CC2=C1C3=C(C=CC=C3)N2)CNCCOC4=CC=CC=C4OC
• InChI: 1S/C24H26N2O4/c1-28-21-10-4-5-11-22(21)29-14-13-25-15-17(27)16-30-23-12-6-9-20-24(23)18-7-2-3-8-19(18)26-20/h2-12,17,25-27H,13-16H2,1H3
• InChI key: OGHNVEJMJSYVRP-UHFFFAOYSA-N
• Gene Information: human ... ADRA1A(148) , ADRA1B(147) , ADRA1D(146) , ADRB1(153) , ADRB2(154) , ADRB3(155)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Carvedilol USP Reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monograph such as Carvedilol Tablets

Biochem/physiol Actions

Cavedilol is a non-selective β-adrenergic blocker with α1 blocking activity. Carvedilol is used specifically for the treatment of heart failure and high blood pressure. It has been shown to improve left ventricular ejection fraction and may reduce mortality.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• pictograms: GHS08,GHS09
• signalword: Warning
• hcodes: H373,H411
• pcodes: P260 - P273 - P314 - P391 - P501
• Hazard Classifications: Aquatic Chronic 2 - STOT RE 2
• target_organs: Liver,spleen,Uterus (including cervix),Adrenal gland
• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable