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Key Documents

1140393

USP

Clonidine

United States Pharmacopeia (USP) Reference Standard

Synonym(s):

2-(2,6-Dichloroanilino)-2-imidazoline

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About This Item

Empirical Formula (Hill Notation):
C9H9Cl2N3
CAS Number:
Molecular Weight:
230.09
UNSPSC Code:
41116107
NACRES:
NA.24

grade

pharmaceutical primary standard

API family

clonidine

manufacturer/tradename

USP

application(s)

pharmaceutical (small molecule)

format

neat

InChI

1S/C9H9Cl2N3/c10-6-2-1-3-7(11)8(6)14-9-12-4-5-13-9/h1-3H,4-5H2,(H2,12,13,14)

InChI key

GJSURZIOUXUGAL-UHFFFAOYSA-N

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application


  • Pharmacological research in hypertension: Clonidine, as an alpha-2 adrenergic agonist, is widely researched for its efficacy in controlling high blood pressure, highlighting its role in cardiovascular studies and its impact on hypertension management (Luo et al., 2023).

  • Neuroscience studies on ADHD: Studies utilizing clonidine in the treatment of Attention Deficit Hyperactivity Disorder (ADHD) emphasize its effectiveness as a non-stimulant option, contributing to neuroscience research by exploring its neuromodulatory effects (Goodwin et al., 2023).

  • Opioid withdrawal management: Clonidine′s application in mitigating opioid withdrawal symptoms underlines its critical role in addiction medicine, providing a pharmacological approach to support recovery processes (Riccardi et al., 2023).

  • Preclinical cardiovascular research: The utilization of clonidine in preclinical studies involves detailed cardiovascular assessments, helping to elucidate the drug′s mechanism in blood pressure regulation and heart rate control, crucial for developing targeted therapies (Salim et al., 2022).

  • In vitro pharmacological profiling: Clonidine is extensively used in in vitro studies for pharmacological profiling, helping to determine its interaction with various neurotransmitter systems and its pharmacodynamics (Flinspach et al., 2022).

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

pictograms

Skull and crossbones

signalword

Danger

hcodes

Hazard Classifications

Acute Tox. 3 Oral

Storage Class

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


Certificates of Analysis (COA)

Search for Certificates of Analysis (COA) by entering the products Lot/Batch Number. Lot and Batch Numbers can be found on a product’s label following the words ‘Lot’ or ‘Batch’.

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