MilliporeSigma

Affinity Chromatography Resins

Affinity chromatography separates complex mixtures through highly selective biochemical interactions. This widely used purification technology efficiently separates a target molecule from impurities. Our range of affinity resins are designed for high throughput and cost-effective purification, from process development through large-scale manufacturing.

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Product Number
Product Name
Product Description
Capacity
Pricing
Capacity
40-55 mg/mL binding capacity
Capacity
~60 mg binding capacity( lysozyme/ml of resin)
Capacity
>75 % binding capacity (anti-A and anti-B)
Capacity
>75 % binding capacity (anti-A and anti-B)
Capacity
~40-55 mg/mL, resin binding capacity((3-6 min RT))
Capacity
~40-55 mg/mL, resin binding capacity((3-6 min RT))
Capacity
~40-55 mg/mL, resin binding capacity((3-6 min RT))
Capacity
~40-55 mg/mL binding capacity((3-6 min RT))
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Protein A Affinity Resins

  • Eshmuno® A is a high-capacity resin for the purification of Fc-containing proteins, such as monoclonal antibodies (mAbs). This resin can be sanitized under acid and alkaline conditions.

Affinity Resins for Plasma Purification

Eshmuno® P anti-A and anti-B resins effectively remove anti-A and anti-B isoagglutinin antibodies in plasma-derived Immunoglobulin (Ig) processes, which has been associated with increased patient risk for hemolysis.

 

Affinity Resins for Protein Purification

Fractogel® Metal Chelate resin offers efficient and cost-effective separation of proteins and peptides, especially proteins with exposed histidine, cysteine, and tryptophan residues, including histidine-tagged proteins.

Support for qualification, risk assessment, and process optimization

Complementing our product portfolio, the Emprove® Program provides three types of dossiers to support different stages of development and manufacturing operations such as qualification, risk assessment, and process optimization. The dossiers consolidate comprehensive product-specific testing data, quality statements, and regulatory information in a readily available format to simplify your compliance needs.


RELATED PRODUCT RESOURCES

mAb Expression, Purification, and Formulation

mAbsizer™ Calculator

Product Selection

Biochromatography Portfolio Guide
Chromatography Purification Selection Guide





Highlights

Webinar: Addressing Immunoglobulin (Ig) Purification Challenges with Chromatographic Technologies
Webinar: Addressing Immunoglobulin (Ig) Purification Challenges with Chromatographic Technologies

Strategies to address Immunoglobulin purification challenges by using Ion Exchange and Affinity chromatography media to enhance both purity & yield.

Webinar: Protein A Affinity Chromatography: How to Capitalize on its Purification Potential
Webinar: Protein A Affinity Chromatography: How to Capitalize on its Purification Potential

Learn productivity & COGs calculations of Protein A affinity chromatography resin at production scale, including best practice strategies to lower costs.

Webinar: Extractables Profiles for Chromatography Resins – Adapted Approach of Upcoming USP
Webinar: Extractables Profiles for Chromatography Resins – Adapted Approach of Upcoming USP

This webinar will cover our study design for extractables profiles of chromatography resins within our Emprove® Program.

Chromatography Supply Program
Chromatography Supply Program

Chromatography Supply Program As a leading partner and supplier to the biopharmaceutical industry, we continue to strengthen our supply chain to help you stay ahead.

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