- The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes.
The CD39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes.
Journal of biomedicine & biotechnology (2012-11-03)
Joanne S J Chia, Jennifer L McRae, Peter J Cowan, Karen M Dwyer
PMID23118504
ABSTRACT
Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73.
MATERIALS
Product Number
Brand
Product Description
Sigma-Aldrich
Apyrase from potatoes, High Activity, ATPase ≥600 units/mg protein, lyophilized powder
Sigma-Aldrich
Apyrase from potatoes, ATPase ≥60 units/mg protein, lyophilized powder (partially purified)