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  • Lanthiopeptin, a new peptide antibiotic. Production, isolation and properties of lanthiopeptin.

Lanthiopeptin, a new peptide antibiotic. Production, isolation and properties of lanthiopeptin.

The Journal of antibiotics (1989-06-01)
N Naruse, O Tenmyo, K Tomita, M Konishi, T Miyaki, H Kawaguchi, K Fukase, T Wakamiya, T Shiba
ABSTRACT

A strain of Streptoverticillium cinnamoneum produced a peptide antibiotic named lanthiopeptin, which contained four unusual amino acids, erythro-beta-hydroxyaspartic acid, mesolanthionine, threo-beta-methyllanthionine and lysinoalanine. Lanthiopeptin showed antiviral activity against herpes simplex virus type 1 KOS strain infection in Vero cells by cytopathic effect reduction assay. The structure of lanthiopeptin is similar to that of ancovenin.

MATERIALS
Product Number
Brand
Product Description

Sigma-Aldrich
Cinnamycin, from Streptomyces cinnamoneus, ≥95% (HPLC)