- Improved Tumor Uptake by Optimizing Liposome Based RES Blockade Strategy.
Improved Tumor Uptake by Optimizing Liposome Based RES Blockade Strategy.
Theranostics (2017-01-04)
Xiaolian Sun, Xuefeng Yan, Orit Jacobson, Wenjing Sun, Zhantong Wang, Xiao Tong, Yuqiong Xia, Daishun Ling, Xiaoyuan Chen
PMID28042337
ABSTRACT
Minimizing the sequestration of nanomaterials (NMs) by the reticuloendothelial system (RES) can enhance the circulation time of NMs, and thus increase their tumor-specific accumulation. Liposomes are generally regarded as safe (GRAS) agents that can block the RES reversibly and temporarily. With the help of positron emission tomography (PET), we monitored the
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