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Synthetic Carbon Adsorbents for Host Cell Protein Removal in Monoclonal Antibody Purification
Demonstration of the excellent capability of Carboxen® synthetic carbon adsorbents to reduce host cell proteins (HCPs) and recover monoclonal antibodies (mAbs) using a post protein A pool step.
Value Drivers and Benefits of Closed Processing
Closed processing enables more streamlined, flexible, and cost-effective multi-product and multi-modal facilities, while ensuring the highest level of product quality and safety. Learn more about how contamination risk is mitigated and the additional value and benefits of closed processing.
One-Batch Calibration: A Process-, Instrument-, Scale- & Site-agnostic Method For Streamlining Raman Implementation
Challenges associated with Raman spectroscopy implementation in bioprocesses can be overcome by the innovative one-batch calibration approach. This streamlined process requires less time and resources compared to traditional approaches, unlocking Raman benefits for biopharmaceutical applications.
Operational and Financial Advantages of Cellicon® Cell Retention Solution in an N-1 Perfusion Process
This page describes the financial and operational advantages offered by the Cellicon® Cell Retention Device in an N-1 perfusion process at the 2,000 L scale in comparison to a cell retention device from another supplier.
Cell Harvest, Lysis, Neutralization and Clarification of Plasmid DNA (pDNA) for mRNA, plasmid-based DNA Vaccines, and Viral Vector applications
An overview of the cell harvest, lysis, neutralization, and clarification steps used for pDNA purification along with case study and practical advice.
Chromatographic Purification of Plasmid DNA (pDNA) for mRNA, Plasmid-based DNA Vaccines, and Viral Vector Applications
See case study examples of how to optimize chromatographic purification of plasmid DNA for Biopharmaceutical Applications.
Plasmid DNA Purification Process
Free eBook outlines plasmid DNA manufacturing process and downstream purification challenges for various applications.
Performance Characteristics of the Mobius® ADC Reactor for Conjugation
ADC production relies on conjugation to link the cytotoxic payload to the mAb. Explore the benefits of a single-use reactor for efficient conjugation.
Improving Efficiency and Control in Biopharma Manufacturing With Process Analytical Technology
Key considerations for process analytical technology (PAT) implementation in biopharma and its role in enabling the facility of the future.
Reproducible Scaling of a Cell Retention Filter Using the Cellicon® Cell Retention Solution
This page describes the design attributes of the Cellicon® filter assembly for cell retention and how they simplify scale-up of intensified upstream processes.
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