Biopolymer Separations
HPLC Columns and Chromatographic Media for the Analysis and Purification of Biopolymers
Biopolymers, including peptides, proteins, polynucleotides, and other biodegradable polymers, vary in terms of net ionic charge, hydrophobicity, size, shape and mass. In addition to these structural (and functional) complexities, an individual biopolymer is typically present at low concentration in samples that contain many similar and similarly complex compounds. Thus, peptides, proteins, and polynucleotides are often analyzed, isolated and purified by multiple modes of chromatography, including size-exclusion, ion-exchange, reversed phase, hydrophobic interaction, hydrophilic interaction, and/or affinity chromatography.
We offer a wide variety of stationary phases for the analysis and purification of large biomolecules, developed and manufactured by Supelco or in cooperation with our technology partners. In addition, we offer columns from well-known brands, including Tosoh Bioscience, Cytiva, Sepax® Technologies and Kromasil.
Our portfolio of U/HPLC and FPLC columns for biopolymer separations is organized by mode of chromatography, and by column brand or manufacturer. Recent additions to the product portfolio include BIOshell™ Glycan columns to determine the glycan composition of glycoproteins, gel-filtration and ion-exchange columns from Sepax® Technologies, and the complete line of TSKgel® HPLC columns and Toyopearl® media and process development columns from Tosoh Bioscience.
Bookmark this page as we continue to add new applications, technical papers and exciting separation tools to advance your biopolymer research.
TSKgel® | |
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TSKgel® Gel Filtration Columns, PW type (T494075) | Product Info. |
TSKgel® Gel Filtration Column, SW type (T494076) | Product Info. |
TSKgel® Ion Exchange Columns (T494077) | Product Info. |
TSKgel® Hydrophobic Interaction Columns (T494078) | Product Info. |
TSKgel® Reversed Phase Columns (T494079) | Product Info. |
TSKgel® Affinity Columns (T494080) | Product Info. |
TSKgel® Nonporous Resin Columns for Rapid Analysis of Proteins, Peptides, and Nucleic Acids - Bulletin 862 (T109862) | Technical Report |
Innovative Approach to Coffee Bean Characterization, Using SEC and High Resolution - Bulletin 919 (T197919) | Technical Report |
Discovery | |
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Discovery® Wide Pore HPLC Columns for Biomolecule separation | Brochure |
Discovery BIO PolyMA: Ion exchange columns for protein and peptide separations (T410079) | Brochure |
Discovery BIO PolyMA: Ion exchange columns for protein and peptide separations (T403118) | Poster |
Enhanced Stability of Discovery BIO Wide Pore C5 Compared to Other Short Alkyl Chain Phases (T103935) | Bulletin 935 |
Getting Started with RP-HPLC for Peptides (T302166) | App Note 166 |
Increase Sensitivity and Decrease Sample Consumption Using HPLC Microbore and Capillary Column Dimensions (T302167) | App Note 167 |
Eliminate TFA and Improve Sensitivity of Peptide Analyses by LC/MS (T302168) | App Note 168 |
Effect of Stationary Phase on Selectivity of Reversed-Phase HPLC Separations of Polypeptides (T302169) | App Note 169 |
Peptide Separations on a Stable, Aqueous Compatible C18 (T403056) | Technical Report |
Kromasil | |
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Kromasil 300 Å for your Protein Separations with Kromasil HPLC Columns (T409220) | Product Info. |
Kromasil 300 Å - SIL, C4, C8, C18 (T409221) | Product Info. |
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