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HomeGas Chromatography (GC) SupraSolv® GC Solvent Specifications

SupraSolv® GC Solvent Specifications

Our GC solvent qualities are ideal for all gas chromatography applications. These solvents are specially developed and tested for ECD, FID and MS detection to ensure a maximum signal-to-noise ratio in the largest specified retention time range. Our solvents for headspace gas chromatography are developed specifically for the analysis of residual solvents in drug substances, excipients, and drug products according to Ph. Eur. and USP. High purity is provided by specially designed production processes for accurate, reliable and reproducible analytical results.

SupraSolv® GC Solvents Specifications

SupraSolv® solventsSupraSolv® Headspace
for analysis of residual solvents
SupraSolv® hypergrade for organic trace analysisSupraSolv®
for GC-ECD/FID
SupraSolv®
for GC-MS
Suitability TestedGC Headspace techniqueElectron capture detector, flame ionization detector and mass spectroscopyElectron capture detector and flame ionization detectorGC-MS/MS
DescriptionsFree from contaminants could possibly interfere with GC analysis by coeluting with peaks of interest in the sampleNarrow specification, the highest purity, and larger retention time range; low boiling substances can be reliably detected; the permissible concentration of interference signals within the retention time range is lowerMeet EPA Method 508 and the stringent demands of capillary gas chromatography; glass-distilled solvents resulting in exceptional quality and low residue levelsUndergo rigorous purification procedures and assure high chemical purity; lowest impurity profile and minimal signal-to-noise ratio in specification
SpecificationEvery residual solvent of class 1 acc. CH ≤ 1 µg/g

Every residual solvent of class 2 acc. CH ≤ 10 µg/g

Every residual solvent of class 3 acc. CH ≤ 50 µg/g

≤ 1 ng/mL compared to Tetrachloromethane GC-ECD

≤ 2 pg/mL compared to Lindane GC-ECD

≤ 2 ng/mL compared to n-Tetradecane GC-FID

≤ 2 ng/mL compared to n-Tetradecane GC-MS
3 pg/mL compared to Lindane GC-ECD

≤ 3 ng/mL compared to n-Tetradecane GC-FID
≤ 3 ng/mL compared to n-Tetradecane GC-MS
BenefitsExtremely high purity resulting in a very low baseline

Microfiltered (0.2 μm)

Packaged under inert gas for longer shelf life

Meet USP, Ph. Eur. and ICH guidelines
Extremely low residual impurities

Multi-purpose grade
Very high purity

Improves column lifetime due to extremely low content of non-volatile matter

low residue levels
Very high purity

Improves column lifetime due to extremely low content of non-volatile matter
ApplicationsResidual solvents analysis in drug substances and products acc. Ph Eur & USPPesticide analysis

Organic residue analysis
Volatile halogenated hydrocarbons in water

Polychlorinated biphenyls (PCB) in water

Detection of Acrylamide in food

BTX analysis (Benzene, Toluene, Xylene) detection

Hydrocarbon-oil-index in water

Determination of emissions in car cockpit materials
Analysis of Dioxins and Furans (PCDD/PCDF)

Analysis of polycyclic aromatic hydrocarbons

Pesticide analysis acc. QuEChERS

Determination of phthalates in plastics

SupraSolv® solvents for gas chromatography ECD and FID

SolventAvailable Pack SizesProduct Number
Acetone1 L GL ,2.5 L GL ,4 L GL ,30 L ST100012
Acetonitrile1L GL ,2.5L GL100017
tert-Butyl methyl ether1 L GL ,2.5 L GL101995
Chloroform, stabilized1 L GL ,2.5 L GL102432
Cyclohexane1 L GL ,2.5 L GL ,4 L GL ,10 L ST102817
Dichloromethane, stabilized1 L GL ,2.5 L GL ,4 L GL ,10 L ST106054
Diethyl ether, stabilized1 L GL ,2.5 L GL ,4 L GL100931
N,N-Dimethylformamide1 L GL ,2.5 L GL110983
Ethanol1 L GL ,2.5 L GL102371
Ethyl acetate
1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST
110972
n-Hexane1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST104371
Isohexane2.5 L GL104340
Isooctane1 L GL ,2.5 L GL115440
Methanol1 L GL ,2.5 L GL,4 L GL106011
n-Pentane1 L GL ,2.5 L GL100882
Petroleum benzine (40 - 60 °C)1 L GL ,2.5 L GL ,4 L GL ,10 L ST,30 L ST101772
2-Propanol1 L GL ,2.5 L GL100998
Toluene1 L GL ,2.5 L GL ,4 L GL108389
Water1 L GL ,2.5 L GL102699

GL = glass bottle I ST = stainless steel barrel I * = sum of hexane isomers + methyl cyclopentane (GC) ≥ 99.8 %
GC-ECD (retention range 1,2,4-Trichlorobenzene to Decachlorobiphenyle individual signals (Lindane standard)) :, 3 pg/mL
GC-FID (retention range n-Undecane to n-Tetracontane individual signals (n-Tetradecane standard)) :, 3 ng/mL


SupraSolv® solvents for gas chromatography MS

SolventAvailable Pack SizesProduct Number
Acetone1L GL, 2.5L GL100658
Acetonitrile1L GL, 2.5L GL100665
Cyclohexane1L GL, 2.5L GL100667
Dichloromethane, stabilized1L GL, 2.5L GL100668
Ethyl acetate1L GL, 2.5L GL100789
n-Hexane1L GL, 2.5L GL100795
Methanol1L GL, 2.5L GL100837
Toluene1L GL, 2.5L GL100849
Water1L GL, 2.5L GL103702
Water, ACS reagent, for ultratrace analysis1L GL14211
1-Methyl-2-pyrrolidinone1L GL43729
Methyl pivalate1L GL52596

GL = glass bottle I * = sum of hexane isomers + methyl cyclopentane (GC) ≥ 99.8 %
GC-MS (retention range n-Undecane to n-Tetracontane; scanning area 30 - 600 amu individual signals (n-Tetradecane standard)) ≤ 3 ng/mL


SupraSolv® headspace for the analysis of residual solvents according to ICH, Ph Eur and USP

SolventAvailable Pack SizesProduct Number
1-Methyl-2-pyrrolidone0.5L GL, 1L GL, 2.5L GL102497
Benzylalcohol1L GL, 2.5L GL102695
N,N-Dimethylacetamide0.5L GL, 1L GL100399
N,N-Dimethylformamide1L GL, 2.5L GL100202
Dimethyl sulfoxide1L GL, 2.5L GL101900
Water1L GL, 2.5L GL100577

GL = glass bottle
Every residual solvent of class 1 acc. CH ≤ 1 μg/g
Every residual solvent of class 2 acc. CH ≤ 10 μg/g
Every residual solvent of class 3 acc. CH ≤ 50 μg/g


SupraSolv® hypergrade solvents for organic trace analysis

SolventAvailable Pack SizesProduct Number
Dichloromethane1L GL106454
n-Hexane1L GL, 2.5L GL104369
n-Pentane1L GL, 2.5L GL107288
Petroleum benzine (40 - 60°C)1L GL, 2.5L GL116740

GL = glass bottle
* Sum of hexane isomers + methylcyclopentane (GC) > 99.9 %
GC-ECD (retention range Dichloromethane to 1,2,4-Trichlorobenzene individual signals (Tetrachloromethane standard)) ≤ 1 ng/mL
GC-ECD (retention range 1,2,4-Trichlorobenzene to Decachlorobiphenyle individual signals (Lindane standard)) ≤ 2 pg/mL
GC-FID (retention range n-Undecane to n-Tetracontane individual signals (n-Tetradecane standard)) ≤ 2 ng/mL
GC-MS (retention range n-Undecane to n-Tetracontane; scanning area 30 - 600 amu individual signals (n-Tetradecane standard) ≤ 2 ng/mL

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