BRAF
v-raf murine sarcoma viral oncogene homolog B
Synonyms:
B-RAF1, BRAF1, NS7, RAFB1
Species:
Human BRAF (673), Mouse Braf (109880), Rat Braf (114486), Horse BRAF (100065760), Zebrafish braf (403065), naked mole-rat Braf (101702762), chicken BRAF (396239), domestic guinea pig Braf (100717765), dog BRAF (475526), domestic cat BRAF (101092346) ...More
UniProtKB ID:
Gene ID:
- Human(673) Summary: This gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(109880) Braf transforming gene
- Rat(114486) v-raf murine sarcoma viral oncogene homolog B
- Horse(100065760) v-raf murine sarcoma viral oncogene homolog B1
- Zebrafish(403065) v-raf murine sarcoma viral oncogene homolog B1
- naked mole-rat(101702762) v-raf murine sarcoma viral oncogene homolog B1
- chicken(396239) v-raf murine sarcoma viral oncogene homolog B1
- domestic guinea pig(100717765) v-raf murine sarcoma viral oncogene homolog B1
- dog(475526) v-raf murine sarcoma viral oncogene homolog B1
- domestic cat(101092346) v-raf murine sarcoma viral oncogene homolog B1
- cow(536051) v-raf murine sarcoma viral oncogene homolog B
- sheep(101107438) v-raf murine sarcoma viral oncogene homolog B1
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-Phospho-B-Raf-T401 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
western blot
Anti-BRAF (V600E) antibody, Rabbit monoclonal, recombinant, expressed in HEK 293 cells, clone RM8, purified immunoglobulin,
Species Reactivity
human
Application
ELISA
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Anti-BRAF (V600E) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-Phospho-BRAF-S445 antibody produced in rabbit, ,
Species Reactivity
human, rat
Application
western blot
Anti-BRAF antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Cell Lines
Product Number
Description
Species
Proteins
Product Number
Description
Species
BRAF (416-766), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human