BRD2
bromodomain containing 2
Synonyms:
D6S113E, FSH, FSRG1, NAT, RING3, RNF3
Species:
Human BRD2 (6046), Mouse Brd2 (14312), Rat Brd2 (294276), domestic guinea pig Brd2 (100734555), cow BRD2 (505358), Domestic Rabbit BRD2 (100343906), domestic cat BRD2 (101084362), sheep BRD2 (101110276), chicken BRD2 (417049), dog BRD2 (474868)
UniProtKB ID:
Gene ID:
- Human(6046) Summary: This gene encodes a transcriptional regulator that belongs to the BET (bromodomains and extra terminal domain) family of proteins. This protein associates with transcription complexes and with acetylated chromatin during mitosis, and it selectively binds to the acetylated lysine-12 residue of histone H4 via its two bromodomains. The gene maps to the major histocompatability complex (MHC) class II region on chromosome 6p21.3, but sequence comparison suggests that the protein is not involved in the immune response. This gene has been implicated in juvenile myoclonic epilepsy, a common form of epilepsy that becomes apparent in adolescence. Multiple alternatively spliced variants have been described for this gene. [provided by RefSeq, Dec 2010]
- Mouse(14312) bromodomain containing 2
- Rat(294276) bromodomain containing 2
- domestic guinea pig(100734555) bromodomain containing 2
- cow(505358) bromodomain containing 2
- Domestic Rabbit(100343906) bromodomain containing 2
- domestic cat(101084362) bromodomain containing 2
- sheep(101110276) bromodomain containing 2
- chicken(417049) bromodomain containing 2
- dog(474868) bromodomain containing 2
- naked mole-rat(101699681) bromodomain containing 2
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-BRD2 antibody produced in mouse, clone 3D10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
western blot
Anti-BRD2 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, mouse, pig, rat
Application
western blot
Rabbit anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human, mouse
Application
immunofluorescence
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-BRD2 Antibody, from rabbit, purified by affinity chromatography,
Species Reactivity
human, rat
Application
immunohistochemistry
western blot
western blot
Goat anti-BRD2 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
BRD2 (339-459) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human
BRD2 (339-459) GST tag human, recombinant, expressed in E. coli, ≥86% (SDS-PAGE),
Species
human
BRD2 (65-187) GST tag human, recombinant, expressed in E. coli, ≥81% (SDS-PAGE),
Species
human
BRD2, BD1, BD2 (65-459) GST tag human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human
BRD2 (65-187) His tag human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human