CBX5
chromobox homolog 5
Synonyms:
HP1, HP1A
Species:
Human CBX5 (23468), Mouse Cbx5 (12419), Rat Cbx5 (300266), sheep CBX5 (100307036), naked mole-rat Cbx5 (101710464), domestic guinea pig Cbx5 (100727253), cow CBX5 (538885), dog CBX5 (477593), Zebrafish cbx5 (563396), domestic cat CBX5 (101091461)
UniProtKB ID:
Gene ID:
- Human(23468) Summary: This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The encoded product is involved in the formation of functional kinetochore through interaction with essential kinetochore proteins. The gene has a pseudogene located on chromosome 3. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
- Mouse(12419) chromobox 5
- Rat(300266) chromobox homolog 5
- sheep(100307036) chromobox homolog 5
- naked mole-rat(101710464) chromobox homolog 5
- domestic guinea pig(100727253) chromobox homolog 5
- cow(538885) chromobox homolog 5
- dog(477593) chromobox homolog 5
- Zebrafish(563396) chromobox homolog 5 (HP1 alpha homolog, Drosophila)
- domestic cat(101091461) chromobox homolog 5
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Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-CBX5 antibody produced in mouse, clone 1E11-3A10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence
western blot
immunofluorescence
western blot
Rabbit anti-CBX5 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot
Anti-Heterochromatin Protein-1 Antibody, clone 4C12.1, clone 4C12.1, from mouse,
Species Reactivity
human, mouse
Application
immunohistochemistry
western blot
western blot
Anti-HP1α Antibody, clone15.19s2, clone 15.19s2, Upstate®, from mouse,
Species Reactivity
human, mouse, vertebrates
Application
ChIP
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunohistochemistry
immunoprecipitation (IP)
western blot
Anti-Heterochromatin Protein-1 α Antibody, clone 2HP-2G9, ascites fluid, clone 2HP-2G9, Chemicon®,
Species Reactivity
human, mouse
Application
ELISA
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot