DNM1L
dynamin 1-like
Synonyms:
DLP1, DRP1, DVLP, DYMPLE, EMPF, HDYNIV
Species:
Human DNM1L (10059), Mouse Dnm1l (74006), Rat Dnm1l (114114), Zebrafish dnm1l (393896), sheep DNM1L (101108646), cow DNM1L (540892), domestic cat DNM1L (101094189), dog DNM1L (477649), naked mole-rat Dnm1l (101713152), domestic guinea pig Dnm1l (100728964)
UniProtKB ID:
Gene ID:
- Human(10059) Summary: This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]
- Mouse(74006) dynamin 1-like
- Rat(114114) dynamin 1-like
- Zebrafish(393896) dynamin 1-like
- sheep(101108646) dynamin 1-like
- cow(540892) dynamin 1-like
- domestic cat(101094189) dynamin 1-like
- dog(477649) dynamin 1-like
- naked mole-rat(101713152) dynamin 1-like
- domestic guinea pig(100728964) dynamin 1-like
- chicken(418132) dynamin 1-like
Custom & Knockdown Gene Products
siRNA
Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.
shRNA
Shop the largest, most validated shRNA collection and build your own clone sets.
Custom Gene Products
We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.
Antibodies
Product Number
Description
Species Reactivity
Application
Anti-phospho-DRP1 (pSer637) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-DNM1L antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-DNM1L antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse
Application
ELISA
immunocytochemistry
immunofluorescence
western blot
immunocytochemistry
immunofluorescence
western blot
Anti-DRP1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
immunohistochemistry
western blot
immunohistochemistry
western blot
Anti-p-DRP1-Ser637 Antibody, clone 5G23 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
bovine, canine, feline, human, monkey, mouse, rat
Application
affinity binding assay
inhibition assay
western blot
inhibition assay
western blot