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GHR

growth hormone receptor

Synonyms:
GHBP
Species:
UniProtKB ID:
Gene ID:
  • Human(2690) Summary: This gene encodes a member of the type I cytokine receptor family, which is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. In humans and rabbits, but not rodents, growth hormone binding protein (GHBP) is generated by proteolytic cleavage of the extracellular ligand-binding domain from the mature growth hormone receptor protein. Multiple alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jun 2011]
  • Mouse(14600) growth hormone receptor
  • Rat(25235) growth hormone receptor
  • dog(403721) growth hormone receptor
  • chicken(408184) growth hormone receptor
  • naked mole-rat(101716037) growth hormone receptor
  • domestic guinea pig(100135527) growth hormone receptor
  • Domestic Rabbit(100009325) growth hormone receptor
  • sheep(443333) growth hormone receptor
  • Goat(100860790) growth hormone receptor
  • cow(280805) growth hormone receptor
  • domestic cat(101093244) growth hormone receptor

Custom & Knockdown Gene Products

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ELISA

Product Number
Description
Species
Human GHR ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-Growth Hormone Receptor antibody produced in goat, affinity isolated antibody, lyophilized powder,
Species Reactivity
mouse
Application
immunohistochemistry
western blot
Anti-GHR antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human
Application
western blot
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunofluorescence
Anti-GHR Mouse mAb (3A12), liquid, clone 3A12, Calbiochem®,
Species Reactivity
human
Application
Anti-GHR antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Species Reactivity
human
Application
immunohistochemistry

Small Molecule - Ligand

Product Number
Description
Species
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Species
human

Proteins

Product Number
Description
Species
GHBP human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE),
Species
human
Somatotropin from human pituitary, recombinant, expressed in E. coli, ≥95% (SDS-PAGE), lyophilized powder,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse Ghr,
Species
mouse
MISSION® esiRNA, targeting human GHR,
Species
human