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ITPR1

inositol 1,4,5-trisphosphate receptor, type 1

Synonyms:
INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29
Species:
UniProtKB ID:
Gene ID:
  • Human(3708) Summary: This gene encodes an intracellular receptor for inositol 1,4,5-trisphosphate. Upon stimulation by inositol 1,4,5-trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene. [provided by RefSeq, Nov 2009]
  • Mouse(16438) inositol 1,4,5-trisphosphate receptor 1
  • Rat(25262) inositol 1,4,5-trisphosphate receptor, type 1
  • cow(317697) inositol 1,4,5-trisphosphate receptor, type 1
  • Zebrafish(100149388) inositol 1,4,5-triphosphate receptor, type 1
  • domestic guinea pig(100713023) inositol 1,4,5-trisphosphate receptor, type 1
  • dog(476548) inositol 1,4,5-trisphosphate receptor, type 1
  • Horse(100052808) inositol 1,4,5-trisphosphate receptor, type 1
  • sheep(101108864) inositol 1,4,5-trisphosphate receptor, type 1
  • sheep(100500722) inositol 1,4,5-trisphosphate receptor, type 1
  • chicken(395412) inositol 1,4,5-trisphosphate receptor, type 1
  • naked mole-rat(101706047) inositol 1,4,5-trisphosphate receptor, type 1
  • domestic cat(101100546) inositol 1,4,5-trisphosphate receptor, type 1

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  • Custom Gene Products

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Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-ITPR1 antibody produced in mouse, clone 2B6, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-ITPR1 antibody produced in mouse, clone S24-18, 1 mg/mL, purified immunoglobulin,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-IP3 Receptor 1 Antibody, Chemicon®, from rabbit,
Species Reactivity
rat
Application
western blot
Anti-IP3 Receptor Antibody, from rabbit,
Species Reactivity
bovine, canine, dog, human, mouse, pig, rabbit, rat
Application
ELISA
immunofluorescence

immunohistochemistry

immunoprecipitation (IP)

radioimmunoassay

western blot
Anti-ITPR1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunohistochemistry
western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human ITPR1,
Species
human
MISSION® esiRNA, targeting mouse Itpr1,
Species
mouse