MYC
v-myc avian myelocytomatosis viral oncogene homolog
Synonyms:
MRTL, MYCC, bHLHe39, c-Myc
Species:
Human MYC (4609), Mouse Myc (17869), Rat Myc (24577), chicken MYC (420332), dog MYC (403924), domestic cat MYC (100379628), cow MYC (511077), sheep MYC (443447), Domestic Rabbit MYC (100327265), domestic guinea pig Myc (100724557)
UniProtKB ID:
Gene ID:
- Human(4609) Summary: The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene. [provided by RefSeq, Jul 2008]
- Mouse(17869) myelocytomatosis oncogene
- Rat(24577) myelocytomatosis oncogene
- chicken(420332) v-myc myelocytomatosis viral oncogene homolog
- dog(403924) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic cat(100379628) v-myc myelocytomatosis viral oncogene homolog (avian)
- cow(511077) v-myc myelocytomatosis viral oncogene homolog (avian)
- sheep(443447) v-myc myelocytomatosis viral oncogene homolog (avian)
- Domestic Rabbit(100327265) v-myc myelocytomatosis viral oncogene homolog (avian)
- domestic guinea pig(100724557) v-myc myelocytomatosis viral oncogene homolog (avian)
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ELISA
Product Number
Description
Species
Antibodies
Product Number
Description
Species Reactivity
Application
Monoclonal Anti-c-Myc tag Biotin produced in mouse, ,
Species Reactivity
Application
flow cytometry
immunohistochemistry
immunoprecipitation (IP)
western blot
immunohistochemistry
immunoprecipitation (IP)
western blot
Monoclonal Anti-c-Myc−Cy3™ antibody produced in mouse, clone 9E10, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
immunofluorescence
Anti-phospho-Myc (pThr358) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-MYC (pThr58) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-c-Myc−Biotin antibody, Mouse monoclonal, clone 9E10, purified from hybridoma cell culture,
Species Reactivity
human
Application
western blot
Proteins
Product Number
Description
Species
C-myc, proto oncogene human, recombinant, expressed in E. coli, ≥80% (SDS-PAGE),
Species
human