Skip to Content
MilliporeSigma

SERPINE1

serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Synonyms:
PAI, PAI-1, PAI1, PLANH1
Species:
UniProtKB ID:
Gene ID:
  • Human(5054) Summary: This gene encodes a member of the serine proteinase inhibitor (serpin) superfamily. This member is the principal inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA), and hence is an inhibitor of fibrinolysis. Defects in this gene are the cause of plasminogen activator inhibitor-1 deficiency (PAI-1 deficiency), and high concentrations of the gene product are associated with thrombophilia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]
  • Mouse(18787) serine (or cysteine) peptidase inhibitor, clade E, member 1
  • Rat(24617) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • cow(281375) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Zebrafish(100136840) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic guinea pig(100725387) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • naked mole-rat(101703903) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • Domestic Rabbit(100009588) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • dog(403476) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1
  • domestic cat(100127105) serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

ELISA

Product Number
Description
Species
Human PAI-1 ELISA Kit, for serum, plasma, cell culture supernatant.,
Species
human
Rhesus Macaque PAI-1 ELISA Kit, for cell culture supernatants, plasma, and serum samples,
Species

Antibodies

Product Number
Description
Species Reactivity
Application
Anti-SERPINE1 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Species Reactivity
human
Application
immunofluorescence
immunohistochemistry
Anti-SerPINE1 (AB1) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, human, mouse, pig, rabbit, rat, sheep
Application
immunohistochemistry
western blot
Anti-SerPINE1 (AB2) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, horse, human, pig, rabbit, rat, sheep
Application
western blot
Anti-SERPINE1 antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
Anti-SERPINE1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunofluorescence
western blot

Proteins

Product Number
Description
Species
Plasminogen activator inhibitor 1 (PAI-1) human, recombinant, expressed in E. coli, ≥90% (SDS-PAGE),
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human SERPINE1,
Species
human
MISSION® esiRNA, targeting mouse Serpine1,
Species
mouse